Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | TTPA | P49638 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8059416 | 0.84 | TYR (0.41) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL7792572 | 0.78 | CTSB (0.45) | CTSBCTSL | |
| SCHEMBL8060477 | 0.74 | TYR (0.41) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL14283899 | 0.73 | CYP3A4 (0.47) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL14283909 | 0.73 | CYP3A4 (0.47) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL5769978 | 0.71 | CYP3A4 (0.46) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL8385341 | 0.71 | PDE4D (0.40) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL7786640 | 0.71 | PTGS1 (0.39) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL1285320 | 0.70 | CYP3A4 (0.44) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL7786645 | 0.69 | POLB (0.41) | CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0909267-B1 | NOVEL 1,3-DIPHENYLPROPANE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST TYROSINASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD (KR) | 2001-11-21 | — | — | EP | disclosed |
| US-6093836-A | INHIBITORY ACTIVITY AGAINT MELANIN BIOSYNTHESIS; WHITENING SUBSTANCES FOR MEDICAMENTS, COSMETICS | LG CHEMICAL LTD. (KR) | 2000-07-25 | — | — | US | disclosed |
| EP-0909267-A1 | NOVEL 1,3-DIPHENYLPROPANE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST TYROSINASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LIMITED (KR) | 1999-04-21 | — | — | EP | disclosed |
| WO-1998039279-A1 | NOVEL 1,3-DIPHENYLPROPANE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST TYROSINASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD. (KR) | 1998-09-11 | — | — | WO | disclosed |