Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | TTPA | P49638 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7792567 | 0.84 | PTGS1 (0.38) | CYP3A4TSHRKMT2AALOX5PDE4D | |
| SCHEMBL7786640 | 0.82 | PTGS1 (0.39) | MAPTCYP3A4TSHRMEN1KMT2A | |
| SCHEMBL7792572 | 0.81 | CTSB (0.45) | — | |
| SCHEMBL8060477 | 0.81 | TYR (0.41) | TYRMAPTCYP3A4TSHRMEN1 | |
| SCHEMBL14283899 | 0.80 | CYP3A4 (0.47) | MAPTCYP3A4TSHRMEN1KMT2A | |
| SCHEMBL1285801 | 0.77 | PTGS1 (0.40) | MAPTCYP3A4TSHRMEN1KMT2A | |
| SCHEMBL5772521 | 0.77 | CYP3A4 (0.43) | MAPTCYP3A4TSHRMEN1KMT2A | |
| SCHEMBL14283909 | 0.75 | CYP3A4 (0.47) | MAPTCYP3A4TSHRMEN1KMT2A | |
| SCHEMBL5769978 | 0.74 | CYP3A4 (0.46) | MAPTCYP3A4TSHRMEN1KMT2A | |
| SCHEMBL5774081 | 0.73 | TTPA (0.49) | MAPTCYP3A4TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093836-A | INHIBITORY ACTIVITY AGAINT MELANIN BIOSYNTHESIS; WHITENING SUBSTANCES FOR MEDICAMENTS, COSMETICS | LG CHEMICAL LTD. (KR) | 2000-07-25 | — | — | US | disclosed |
| EP-0909267-A1 | NOVEL 1,3-DIPHENYLPROPANE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST TYROSINASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LIMITED (KR) | 1999-04-21 | — | — | EP | disclosed |
| WO-1998039279-A1 | NOVEL 1,3-DIPHENYLPROPANE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST TYROSINASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD. (KR) | 1998-09-11 | — | — | WO | disclosed |