Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.32 |
| ▸ | TTPA | P49638 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8060477 | 0.76 | TYR (0.41) | PDE4DPTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL7792567 | 0.71 | PTGS1 (0.38) | PDE4DPTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL5768105 | 0.70 | CYP3A4 (0.44) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL7792572 | 0.70 | CTSB (0.45) | CTSB | |
| SCHEMBL8386678 | 0.69 | GAA (0.35) | CYP3A4MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8059416 | 0.69 | TYR (0.41) | PDE4DPTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL7792676 | 0.68 | TTPA (0.35) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL8386674 | 0.68 | CA12 (0.39) | LMNAMEN1KMT2A | |
| SCHEMBL8385360 | 0.67 | GAA (0.35) | CYP3A4MAPTMEN1KMT2AKDM4E | |
| Apc-100 SCHEMBL633424 | 0.67 | CYP3A4 (0.64) | PTGS1PTGS2CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0909267-A1 | NOVEL 1,3-DIPHENYLPROPANE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST TYROSINASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LIMITED (KR) | 1999-04-21 | — | — | EP | disclosed |
| WO-1998039279-A1 | NOVEL 1,3-DIPHENYLPROPANE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST TYROSINASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD. (KR) | 1998-09-11 | — | — | WO | disclosed |