Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 7/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
| ▸ | TTPA | P49638 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7792676 | 0.82 | TTPA (0.35) | MAPTLMNAMEN1KMT2AGSTP1 | |
| SCHEMBL8059416 | 0.81 | TYR (0.41) | TYRPDE4DMALT1MAPTLMNA | |
| SCHEMBL7792572 | 0.78 | CTSB (0.45) | — | |
| SCHEMBL8385341 | 0.76 | PDE4D (0.40) | PDE4DMALT1MAPTLMNAMEN1 | |
| SCHEMBL8063175 | 0.76 | TYR (0.58) | TYRMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL7792567 | 0.74 | PTGS1 (0.38) | PDE4DMALT1KMT2ATTPANR1I2 | |
| SCHEMBL5768105 | 0.72 | CYP3A4 (0.44) | MAPTLMNAMEN1KMT2AGSTP1 | |
| SCHEMBL8059449 | 0.70 | TYR (0.50) | TYRMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL8063169 | 0.68 | TYR (0.50) | TYRMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL14283899 | 0.67 | CYP3A4 (0.47) | MAPTLMNAMEN1KMT2AGSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093836-A | INHIBITORY ACTIVITY AGAINT MELANIN BIOSYNTHESIS; WHITENING SUBSTANCES FOR MEDICAMENTS, COSMETICS | LG CHEMICAL LTD. (KR) | 2000-07-25 | — | — | US | disclosed |