Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.40 |
| ▸ | MAOB | P27338 | 6/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5012369 | 0.98 | MAOA (0.39) | MAOAMAOBCES1ESR1POLB | |
| SCHEMBL14123664 | 0.98 | MAOA (0.39) | MAOAMAOBCES1ESR1POLB | |
| SCHEMBL5008736 | 0.98 | MAOA (0.39) | MAOAMAOBCES1ESR1POLB | |
| SCHEMBL7791505 | 0.94 | MAOA (0.41) | MAOAMAOBCES1ESR1POLB | |
| SCHEMBL7790765 | 0.81 | MAOA (0.37) | MAOAMAOBCES1ESR1POLB | |
| SCHEMBL7792764 | 0.78 | ESR1 (0.47) | MAOAMAOBCES1ESR1CYP3A4 | |
| SCHEMBL8396822 | 0.77 | MAOA (0.42) | MAOAMAOBCES1ESR1POLB | |
| SCHEMBL7783038 | 0.76 | MAOA (0.39) | MAOAMAOBCES1ESR1NPSR1 | |
| SCHEMBL8624256 | 0.76 | MAOA (0.33) | MAOAMAOB | |
| SCHEMBL20690145 | 0.75 | MAOA (0.42) | MAOAMAOBCES1POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0890636-B1 | Culture vessel | MENICON CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-6018001-A | ACID TREATMENT OF A CONTACT LENS WHICH IS A COPOLYMER OF ASUGAR KETAL-CONTAINING (METH)ACRYLATE AND A SUGAR GLYCEROL KETAL-CONTAINING (METH)ACRYLATE AND A CO-MONOMER CONTAINING SILICON AND FLUORINE-MONOMER; OXYGEN PERMEABILITY | MENICON CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0892297-A1 | PROCESS FOR PRODUCING CONTACT LENS WITH HYDROPHILIC SURFACE AND CONTACT LENS OBTAINED THEREBY | MENICON CO., LTD. (JP) | 1999-01-20 | — | — | EP | disclosed |
| EP-0890636-A1 | Culture vessel | Menicon Co., Ltd. (JP) | 1999-01-13 | — | — | EP | disclosed |