Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623551 | 0.83 | MAOA (0.38) | MAOAMAOBHDAC1HDAC2SMN1; SMN2 | |
| SCHEMBL8625967 | 0.80 | MAOA (0.36) | MAOAMAOBSMN1; SMN2 | |
| SCHEMBL7792771 | 0.76 | MAOA (0.40) | MAOAMAOB | |
| SCHEMBL5008736 | 0.74 | MAOA (0.39) | MAOAMAOB | |
| SCHEMBL5012369 | 0.74 | MAOA (0.39) | MAOAMAOB | |
| SCHEMBL14123664 | 0.74 | MAOA (0.39) | MAOAMAOB | |
| SCHEMBL8621299 | 0.74 | ALDH1A1 (0.42) | MAOAMAOB | |
| SCHEMBL3752087 | 0.73 | MAOA (0.50) | MAOAMAOBSMN1; SMN2 | |
| SCHEMBL1996726 | 0.73 | TDP1 (0.54) | SMN1; SMN2 | |
| SCHEMBL13295231 | 0.72 | MAOA (0.42) | MAOAMAOBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786434-A | A CURABLE COPOLYMER COMPRISING A DIALKYLACRYLAMIDE OR METHACRYLAMIDE, A VINYLLACTAM, A BIS(SILICON-CONTAINING ALKYL)FUMARATE MONOMERS; RADIATION TRANSPARENT, HIGH OXYGEN PERMEABILITY | MENICON CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |