SCHEMBL7792764

SCHEMBL7792764

C=C(CC(F)(F)F)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.47
MAOA P21397 6/20 0.47
MAOB P27338 6/20 0.47
CES1 P23141 2/20 0.41
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34
MAPK1 P28482 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8396822 0.81 MAOA (0.42) ESR1MAOAMAOBCES1MEN1
SCHEMBL23287920 0.81 MAOA (0.42) ESR1MAOAMAOBCES1
SCHEMBL7791505 0.79 MAOA (0.41) ESR1MAOAMAOBCES1CYP3A4
SCHEMBL7787989 0.79 MAOA (0.41) ESR1MAOAMAOBCES1MAPT
SCHEMBL28982625 0.78 CES2 (0.48) ESR1CES1MEN1HPGDKMT2A
SCHEMBL10523994 0.78 MAOA (0.44) ESR1MAOAMAOBCES1MAPT
SCHEMBL28639828 0.78 CES1 (0.53) MAOAMAOBCES1KDM4EMEN1
SCHEMBL7792771 0.78 MAOA (0.40) ESR1MAOAMAOBCES1CYP3A4
SCHEMBL2399414 0.77 MAOA (0.47) MAOAMAOBMEN1MAPTHPGD
SCHEMBL10486356 0.77 MAOA (0.47) MAOAMAOBCES1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112500517-A Oil-soluble super-heavy oil viscosity reducer and preparation method and application thereof 山东德仕化工有限公司 2021-03-16 CN disclosed
CN-105980917-B Thermosetting composition having photo-alignment properties, alignment layer, substrate with alignment layer, phase difference plate, and device 大日本印刷株式会社 2019-08-23 CN disclosed
CN-106030395-B Heat-curable composition, oriented layer with light orientation, the substrate with oriented layer, phase plate and device 大日本印刷株式会社 2019-08-23 CN disclosed
CN-105980919-B Heat-curable composition, oriented layer with light orientation, the substrate with oriented layer, phase plate and device 大日本印刷株式会社 2019-08-20 CN disclosed
WO-2018097273-A1 SALTS OF INDAZOLE DERIVATIVE AND CRYSTALS THEREOF EISAI R&D MANAGEMENT CO., LTD. (JP) 2018-05-31 WO disclosed
CN-106030395-A Thermosetting composition having photo-alignment properties, alignment layer, substrate with alignment later, phase difference plate, and device 大日本印刷株式会社 2016-10-12 CN disclosed
CN-105980917-A Thermosetting composition having photo-alignment properties, alignment layer, substrate with alignment layer, phase difference plate, and device 大日本印刷株式会社 2016-09-28 CN disclosed
CN-105980919-A THERMOSETTING COMPOSITION HAVING PHOTO-ALIGNMENT PROPERTIES, ALIGNMENT LAYER, SUBSTRATE WITH ALIGNMENT LAYER, RETARDATION PLATE AND DEVICE 大日本印刷株式会社 2016-09-28 CN disclosed
US-8860076-B2 Optical semiconductor sealing curable composition and optical semiconductor apparatus using this SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-10-14 US disclosed
US-8440777-B2 Addition-cure fluoropolyether adhesive composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-05-14 US disclosed
US-20110178263-A1 ADDITION-CURE FLUOROPOLYETHER ADHESIVE COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-07-21 US disclosed
CN-100412161-C Liquid crystal aligning agent and liquid crystal display element JSR CORP (JP) 2008-08-20 CN disclosed
CN-100344731-C Liquid crystal aligning agent and liquid crystal display element JSR CORP (JP) 2007-10-24 CN disclosed
CN-1721502-A Liquid crystal aligning agent and liquid crystal display element JSR CORP (JP) 2006-01-18 CN disclosed
CN-1408817-A Liquid crystal aligning agent and liquid crystal display element JSR CORP (JP) 2003-04-09 CN disclosed
EP-0890636-B1 Culture vessel MENICON CO LTD (JP) 2001-10-31 EP disclosed
US-6018001-A ACID TREATMENT OF A CONTACT LENS WHICH IS A COPOLYMER OF ASUGAR KETAL-CONTAINING (METH)ACRYLATE AND A SUGAR GLYCEROL KETAL-CONTAINING (METH)ACRYLATE AND A CO-MONOMER CONTAINING SILICON AND FLUORINE-MONOMER; OXYGEN PERMEABILITY MENICON CO., LTD. (JP) 2000-01-25 US disclosed
EP-0892297-A1 PROCESS FOR PRODUCING CONTACT LENS WITH HYDROPHILIC SURFACE AND CONTACT LENS OBTAINED THEREBY MENICON CO., LTD. (JP) 1999-01-20 EP disclosed
EP-0890636-A1 Culture vessel Menicon Co., Ltd. (JP) 1999-01-13 EP disclosed
US-5786434-A A CURABLE COPOLYMER COMPRISING A DIALKYLACRYLAMIDE OR METHACRYLAMIDE, A VINYLLACTAM, A BIS(SILICON-CONTAINING ALKYL)FUMARATE MONOMERS; RADIATION TRANSPARENT, HIGH OXYGEN PERMEABILITY MENICON CO., LTD. (JP) 1998-07-28 US disclosed