Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL7802678 | 0.88 | CYP1A2 (0.42) | CYP1A2ALDH1A1KMT2AMEN1RAB9A | |
| Cyclohexylamine SCHEMBL8037514 | 0.82 | GRIK1 (0.42) | CYP1A2ALDH1A1KMT2AMEN1RAB9A | |
| Cyclohexylamine SCHEMBL8037511 | 0.82 | GRIK1 (0.42) | CYP1A2ALDH1A1KMT2AMEN1RAB9A | |
| Cyclohexylamine SCHEMBL7800230 | 0.81 | ALDH1A1 (0.41) | ALDH1A1KDM4ESMN1; SMN2KMT2ARAB9A | |
| 4-Hydroxybenzaldehyde SCHEMBL7798433 | 0.81 | ALDH5A1 (0.59) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| Cyclohexylamine SCHEMBL7797971 | 0.81 | CYP2A6 (0.59) | CYP1A2ALDH1A1KDM4ESMN1; SMN2KMT2A | |
| Benzaldehyde SCHEMBL8035182 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KDM4ESMN1; SMN2MAPK1KDM1A | |
| Cycloheptanamine SCHEMBL7792128 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KDM4ESMN1; SMN2MAPK1KDM1A | |
| Cyclohexylamine SCHEMBL7800151 | 0.80 | ALDH1A1 (0.65) | ALDH1A1KMT2AMEN1KDM1AMAOA | |
| Cyclohexylamine SCHEMBL7798264 | 0.79 | ALDH1A1 (0.43) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |