Cyclohexylamine

Cyclohexylamine

SCHEMBL8037511

NC1CCCCC1.NC[C@H](N)C(=O)O.O=Cc1ccc(Br)cc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 5/20 0.42
GRIK2 Q13002 4/20 0.42
DPEP1 P16444 1/20 0.41
CYP1A2 P05177 1/20 0.38
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
RAB9A P51151 3/20 0.35
NPC1 O15118 2/20 0.35
KIF11 P52732 3/20 0.35
ALDH1A1 P00352 1/20 0.34
AAK1 Q2M2I8 1/20 0.33
GPR183 P32249 1/20 0.33
DPP4 P27487 1/20 0.32
FAP Q12884 1/20 0.32
DPP8 Q6V1X1 1/20 0.32
DPP9 Q86TI2 1/20 0.32
DPP7 Q9UHL4 1/20 0.32
GRIK3 Q13003 1/20 0.32
ATM Q13315 1/20 0.32
EPHX1 P07099 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexylamine SCHEMBL8037514 1.00 GRIK1 (0.42) GRIK1GRIK2DPEP1CYP1A2KMT2A
4-Hydroxybenzaldehyde SCHEMBL8037281 0.89 ALDH5A1 (0.41) GRIK1GRIK2KMT2AMEN1RAB9A
4-Hydroxybenzaldehyde SCHEMBL8037276 0.89 ALDH5A1 (0.41) GRIK1GRIK2KMT2AMEN1RAB9A
Benzaldehyde SCHEMBL8035694 0.88 KIF11 (0.42) GRIK1GRIK2KMT2AMEN1KIF11
Cyclohexylamine SCHEMBL8037697 0.88 GRIK1 (0.41) GRIK1GRIK2DPEP1KMT2ARAB9A
Cyclohexylamine SCHEMBL8037696 0.88 GRIK1 (0.41) GRIK1GRIK2DPEP1KMT2ARAB9A
Cyclohexylamine SCHEMBL8037421 0.88 ALDH1A1 (0.47) GRIK1GRIK2KMT2ARAB9AKIF11
Cyclohexylamine SCHEMBL8037416 0.88 ALDH1A1 (0.47) GRIK1GRIK2KMT2ARAB9AKIF11
Lysine SCHEMBL8037285 0.87 GSR (0.44) GRIK1GRIK2DPEP1CYP1A2KMT2A
Lysine SCHEMBL8037288 0.87 GSR (0.44) GRIK1GRIK2DPEP1CYP1A2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6127381-A A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY LION BIOSCIENCE AG (DE) 2000-10-03 US disclosed