Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.51 |
| ▸ | KIT | P10721 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793551 | 1.00 | MAOB (0.60) | MAOBRAB9AKDM4ENPC1MAPT | |
| SCHEMBL7793555 | 0.89 | RAB9A (0.52) | MAOBRAB9AKDM4ENPC1MAPT | |
| SCHEMBL7799187 | 0.89 | RAB9A (0.52) | MAOBRAB9AKDM4ENPC1MAPT | |
| SCHEMBL8582883 | 0.77 | PTGS2 (0.55) | MAOBRAB9AKDM4ENPC1MAPT | |
| SCHEMBL19462722 | 0.76 | MAOB (0.87) | MAOBRAB9AKDM4ENPC1MAPT | |
| SCHEMBL26767255 | 0.75 | METAP1 (0.54) | MAOBRAB9AKDM4ENPC1MAPT | |
| SCHEMBL16334358 | 0.74 | MAOB (0.51) | MAOBKDM4ESMN1; SMN2PTGS2ALDH1A1 | |
| SCHEMBL6427553 | 0.74 | MAOB (0.84) | MAOBRAB9AKDM4ENPC1PTGS2 | |
| SCHEMBL6427555 | 0.74 | MAOB (0.84) | MAOBRAB9AKDM4ENPC1PTGS2 | |
| SCHEMBL19789802 | 0.73 | MAOB (0.47) | MAOBRAB9AKDM4ENPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900255-B1 | DONOR-SUBSTITUTED OXINDIGO DERIVATIVES AND THEIR USE AS COLOURANTS | CIBA SC HOLDING AG (CH) | 2001-12-19 | — | — | EP | disclosed |
| US-6156914-A | Donor-substituted oxindigo derivatives and their use as colorants | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-12-05 | — | — | US | disclosed |
| EP-0900255-A1 | DONOR-SUBSTITUTED OXINDIGO DERIVATIVES AND THEIR USE AS COLOURANTS | Ciba SC Holding AG (CH) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997041176-A1 | DONOR-SUBSTITUTED OXINDIGO DERIVATIVES AND THEIR USE AS COLOURANTS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1997-11-06 | — | — | WO | disclosed |