Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | MAOB | P27338 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | STK17B | O94768 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | POR | P16435 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7799187 | 1.00 | RAB9A (0.52) | RAB9AMAOBKDM4ENPC1MAPT | |
| SCHEMBL7793547 | 0.89 | MAOB (0.60) | RAB9AMAOBKDM4ENPC1MAPT | |
| SCHEMBL7793551 | 0.89 | MAOB (0.60) | RAB9AMAOBKDM4ENPC1MAPT | |
| SCHEMBL383503 | 0.77 | CA2 (0.52) | RAB9AMAOBKDM4ENPC1MAPT | |
| SCHEMBL7799402 | 0.73 | MAOB (0.41) | RAB9AMAOBKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL7793695 | 0.73 | MAOB (0.41) | RAB9AMAOBKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL7793689 | 0.73 | MAOB (0.41) | RAB9AMAOBKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL7802429 | 0.71 | ALDH1A1 (0.46) | RAB9AMAOBKDM4ENPC1MAPT | |
| SCHEMBL7801121 | 0.71 | ALDH1A1 (0.46) | RAB9AMAOBKDM4ENPC1MAPT | |
| SCHEMBL7803302 | 0.71 | ALDH1A1 (0.46) | RAB9AMAOBKDM4ENPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900255-B1 | DONOR-SUBSTITUTED OXINDIGO DERIVATIVES AND THEIR USE AS COLOURANTS | CIBA SC HOLDING AG (CH) | 2001-12-19 | — | — | EP | disclosed |
| US-6156914-A | Donor-substituted oxindigo derivatives and their use as colorants | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-12-05 | — | — | US | disclosed |