Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 13/20 | 0.64 |
| ▸ | RARG | P13631 | 12/20 | 0.64 |
| ▸ | RXRA | P19793 | 5/20 | 0.64 |
| ▸ | RARA | P10276 | 13/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 2/20 | 0.46 |
| ▸ | RXRG | P48443 | 2/20 | 0.46 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5845401 | 0.91 | RARB (0.57) | RARBRARGRXRARARAPDK2 | |
| SCHEMBL7794229 | 0.84 | RARB (0.75) | RARBRARGRXRARARARXRB | |
| SCHEMBL7565094 | 0.84 | RARB (0.62) | RARBRARGRXRARARAPDK2 | |
| SCHEMBL2095481 | 0.79 | RXRA (0.57) | RARBRARGRXRARARARXRB | |
| SCHEMBL7793710 | 0.78 | RARB (0.62) | RARBRARGRXRARARA | |
| SCHEMBL9190381 | 0.78 | RARA (0.53) | RARBRARGRXRARARARXRB | |
| SCHEMBL10834477 | 0.78 | RARB (0.59) | RARBRARGRXRARARARXRB | |
| SCHEMBL6730349 | 0.77 | RARB (0.61) | RARBRARGRXRARARAPDK2 | |
| SCHEMBL10549628 | 0.77 | RARG (0.57) | RARBRARGRXRARARARXRB | |
| SCHEMBL7794231 | 0.76 | RARB (0.64) | RARBRARGRXRARARARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316009-B1 | FOR THERAPY OF DERMATOLOGICAL COMPLAINTS ASSOCIATED WITH A KERATINIZATION DISORDER, AND FOR COMBATING AGEING OF THE SKIN | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2001-11-13 | — | — | US | disclosed |