Bicarbonate

Bicarbonate

SCHEMBL7793818

C=CC.COOC(=O)OOC.O=C(O)O

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propene SCHEMBL7156036 0.92 ALDH1A1 (0.32) ALDH1A1
Bicarbonate SCHEMBL28078596 0.86 CA1 (0.36) ALDH1A1
Bicarbonate SCHEMBL28800487 0.80 LMNA (0.41) LMNAALDH1A1
SCHEMBL919091 0.80
Bicarbonate SCHEMBL5134303 0.78 HCAR2 (0.36) LMNAALDH1A1
Bicarbonate SCHEMBL226943 0.76 LMNA (0.50) LMNAALDH1A1
Bicarbonate SCHEMBL28734227 0.76 LMNA (0.50) LMNAALDH1A1
Bicarbonate SCHEMBL29150348 0.76 LMNA (0.50) LMNAALDH1A1
Bicarbonate SCHEMBL20954184 0.76 LMNA (0.50) LMNAALDH1A1
Bicarbonate SCHEMBL21612732 0.76 LMNA (0.50) LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6310960-B1 Rechargeable hearing aid system RESEARCH INTERNATIONAL, INC. 2001-10-30 US disclosed
US-6265100-B1 Rechargeable battery RESEARCH INTERNATIONAL, INC. 2001-07-24 US disclosed