Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7865025 | 0.82 | GABRA1 (0.41) | GABRA1GABRB2ALDH1A1ADRB2ADRB1 | |
| SCHEMBL7790995 | 0.81 | ADRB2 (0.39) | ADRB2ADRB1LMNAADRB3HTR1A | |
| SCHEMBL7791009 | 0.79 | NTRK1 (0.35) | GABRA1GABRB2ALDH1A1KDM4EKMT2A | |
| SCHEMBL7793925 | 0.77 | PRKCA (0.32) | — | |
| SCHEMBL7785310 | 0.76 | USP1 (0.31) | — | |
| SCHEMBL7790883 | 0.75 | CYP3A4 (0.50) | ALDH1A1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL9289369 | 0.73 | GABRA1 (0.44) | GABRA1GABRB2TSHRKDM4ETDP1 | |
| SCHEMBL5139620 | 0.73 | GABRA1 (0.48) | GABRA1GABRB2ALDH1A1HTR1AADRA2C | |
| SCHEMBL8517500 | 0.72 | ADRB2 (0.39) | GABRA1GABRB2ALDH1A1ADRB2ADRB1 | |
| SCHEMBL2362466 | 0.67 | GABRA1 (0.61) | GABRA1GABRB2ALDH1A1LMNAHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435632-B1 | Phenylpyrimidine derivatives, process for preparing the same, liquid crystal compositions containing said derivatives as active ingredient, and liquid crystal elements using such compositions | SUMITOMO CHEMICAL CO (JP) | 2001-11-28 | — | — | EP | disclosed |
| EP-1067122-A2 | Phenylpyrimidine derivatives, process for preparing the same, liquid crystal compositions containing said derivatives as active ingredient, and liquid crystal elements using such compositions | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-10 | — | — | EP | disclosed |
| US-5723610-A | Alcohol reactants for forming phenylpyrimidine derivatives and process for preparing said alcohols | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-03-03 | — | — | US | disclosed |
| US-5539115-A | FERROELECTRIC CRYSTALS FOR OPTICAL APPARATUS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0435632-A2 | Phenylpyrimidine derivatives, process for preparing the same, liquid crystal compositions containing said derivatives as active ingredient, and liquid crystal elements using such compositions | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-07-03 | — | — | EP | disclosed |