Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | UGCG | Q16739 | 3/20 | 0.35 |
| ▸ | GBA2 | Q9HCG7 | 3/20 | 0.35 |
| ▸ | GBA1 | P04062 | 2/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795363 | 0.90 | ALDH1A1 (0.38) | APPPTPN2PTPN1PTPN6ALDH1A1 | |
| SCHEMBL316600 | 0.84 | ALDH1A1 (0.46) | ALDH1A1UGCGGBA2GBA1SI | |
| SCHEMBL316695 | 0.84 | ALDH1A1 (0.46) | PTPN2PTPN1PTPN6ALDH1A1TEAD3 | |
| SCHEMBL18868387 | 0.83 | ALDH1A1 (0.44) | ALDH1A1UGCGGBA2GBA1SI | |
| SCHEMBL18832287 | 0.80 | ALDH1A1 (0.50) | PTPN2PTPN1PTPN6ALDH1A1TEAD3 | |
| SCHEMBL7794936 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL9314684 | 0.79 | ALDH1A1 (0.31) | ALDH1A1TDP1L3MBTL1CHRNB2CHRNB4 | |
| SCHEMBL17075233 | 0.79 | ALDH1A1 (0.48) | APPPTPN2PTPN1PTPN6ALDH1A1 | |
| SCHEMBL1140820 | 0.79 | ALDH1A1 (0.48) | APPPTPN2PTPN1PTPN6ALDH1A1 | |
| SCHEMBL13626326 | 0.78 | CHRNB2 (0.50) | APPALDH1A1MAOBCHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729041-B1 | Water-Absorptive soft contact lens | MENICON CO LTD (JP) | 2001-11-28 | — | — | EP | disclosed |
| US-5741830-A | COPOLYMER OF A FLUORINE CONTAINING STYRENE DERIVATIVE AND N,N-DIMETHYL(METH)ACRYLAMIDE | MENICON CO., LTD. (JP) | 1998-04-21 | — | — | US | disclosed |
| EP-0729041-A2 | Water-Absorptive soft contact lens | Menicon Co., Ltd. (JP) | 1996-08-28 | — | — | EP | disclosed |