Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.55 |
| ▸ | SHBG | P04278 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | PGR | P06401 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | AR | P10275 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6707178 | 0.88 | CYP19A1 (0.58) | CYP19A1SHBGLMNANR3C1CYP2C19 | |
| SCHEMBL7795449 | 0.79 | SHBG (0.48) | CYP19A1SHBGLMNANR3C1CYP2C19 | |
| SCHEMBL10518162 | 0.73 | LMNA (0.62) | SHBGLMNANR3C1CYP2C19SMN1; SMN2 | |
| SCHEMBL10518166 | 0.73 | LMNA (0.62) | SHBGLMNANR3C1CYP2C19SMN1; SMN2 | |
| SCHEMBL3507483 | 0.73 | SHBG (0.67) | CYP19A1SHBGLMNANR3C1CYP2C19 | |
| SCHEMBL3507486 | 0.73 | SHBG (0.67) | CYP19A1SHBGLMNANR3C1CYP2C19 | |
| SCHEMBL10959915 | 0.72 | SHBG (0.65) | CYP19A1SHBGLMNANR3C1CYP2C19 | |
| SCHEMBL10959929 | 0.72 | SHBG (0.65) | CYP19A1SHBGLMNANR3C1CYP2C19 | |
| SCHEMBL7797159 | 0.72 | PGR (0.71) | CYP19A1LMNANR3C1CYP2C19SMN1; SMN2 | |
| SCHEMBL10939403 | 0.72 | CYP19A1 (1.00) | CYP19A1SHBGLMNASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863760-B1 | USE OF ANTIMINERALOCORTICOID COMPOUNDS AGAINST DRUG WITHDRAWAL SYNDROME | AVENTIS PHARMA SA (FR) | 2001-12-05 | — | — | EP | claimed |