Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11516735 | 0.79 | TSHR (0.44) | TSHRHSD17B10SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL11519652 | 0.73 | ALDH1A1 (0.43) | DCTPP1TSHRHSD17B10CYP1A2SMN1; SMN2 | |
| SCHEMBL11508254 | 0.72 | TSHR (0.40) | TSHRHSD17B10CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL11510417 | 0.71 | TDP1 (0.53) | TSHRHSD17B10CYP1A2SMN1; SMN2ALDH1A1 | |
| Phenol SCHEMBL27604479 | 0.70 | TSHR (0.45) | DCTPP1TSHRHSD17B10CYP1A2SMN1; SMN2 | |
| SCHEMBL2777976 | 0.70 | TSHR (0.45) | TSHRHSD17B10CYP1A2ALDH1A1TDP1 | |
| SCHEMBL27801030 | 0.69 | CYP1A2 (0.42) | TSHRCYP1A2SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL304097 | 0.69 | CYP1A2 (0.57) | TSHRHSD17B10CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL2581016 | 0.69 | CYP1A2 (0.62) | TSHRHSD17B10CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL11520195 | 0.68 | ALDH1A1 (0.35) | HSD17B10ALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870756-B1 | Process for the preparation of 3,4-disubstituted dinitroanilines | CFPI NUFARM (FR) | 2001-11-07 | — | — | EP | disclosed |
| US-6028226-A | Process for 3,4-disubstituted dinitroanilines | CFPI AGRO (FR) | 2000-02-22 | — | — | US | disclosed |
| EP-0870756-A1 | Process for the preparation of 3,4-disubstituted dinitroanilines | CFPI AGRO (FR) | 1998-10-14 | — | — | EP | disclosed |