SCHEMBL7794724

SCHEMBL7794724

COC(C)OC.Cc1cc(C=O)ccc1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.41
NPC1 O15118 1/20 0.40
CYP2C9 P11712 1/20 0.40
RAB9A P51151 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TRIM24 O15164 2/20 0.38
TRIM33 Q9UPN9 2/20 0.38
AOX1 Q06278 1/20 0.38
HPGD P15428 1/20 0.38
ALDH5A1 P51649 1/20 0.38
ABAT P80404 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TSHR P16473 1/20 0.38
RXRB P28702 2/20 0.37
UNG P13051 1/20 0.37
RXRA P19793 1/20 0.36
ALDH1A3 P47895 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL102841 0.87 ALDH1A1 (0.52) ALDH1A1NPC1CYP2C9RAB9ANPSR1
SCHEMBL29907874 0.81 ALDH1A1 (0.68) ALDH1A1CYP2C9NPSR1HPGDTDP1
SCHEMBL3876084 0.79 ALDH1A1 (0.68) ALDH1A1TRIM24TRIM33HPGDTDP1
SCHEMBL28914427 0.78 ALDH1A1 (0.54) ALDH1A1TDP1RXRBRXRA
SCHEMBL497789 0.76 ALDH1A1 (0.59) ALDH1A1CYP2C9RAB9ATRIM24TRIM33
SCHEMBL5275314 0.74 ALDH1A3 (0.42) ALDH1A1NPC1RAB9ATRIM24TRIM33
SCHEMBL4613992 0.74 ALDH1A1 (0.52) ALDH1A1NPC1CYP2C9RAB9ANPSR1
SCHEMBL30589393 0.74 ALDH1A1 (0.52) ALDH1A1NPC1CYP2C9RAB9ANPSR1
SCHEMBL30901985 0.73 ALDH1A1 (0.47) ALDH1A1NPC1CYP2C9RAB9ANPSR1
SCHEMBL10893340 0.73 ALDH1A1 (0.47) ALDH1A1NPC1CYP2C9RAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1150689-A1 CHEMICAL COMPOUNDS NORSK HYDRO ASA (NO) 2001-11-07 EP disclosed
WO-2000048609-A1 CHEMICAL COMPOUNDS NORSK HYDRO ASA (NO) 2000-08-24 WO disclosed