Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3509685 | 0.86 | ALDH1A1 (0.55) | ALDH1A1HPGDMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL16956580 | 0.86 | KDM4E (0.46) | ALDH1A1HPGDMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL5033639 | 0.85 | ALDH1A1 (0.58) | ALDH1A1HPGDMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL11469172 | 0.85 | ALDH1A1 (0.58) | ALDH1A1HPGDMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL29907874 | 0.84 | ALDH1A1 (0.68) | ALDH1A1HPGDMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL24861874 | 0.84 | KDM4E (0.45) | ALDH1A1HPGDMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL10165329 | 0.84 | KDM4E (0.45) | ALDH1A1HPGDMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL28763812 | 0.83 | PTGS2 (0.49) | ALDH1A1HPGDMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL28763808 | 0.83 | PTGS2 (0.49) | ALDH1A1HPGDMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL18432645 | 0.83 | PTGS2 (0.49) | ALDH1A1HPGDMAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122059949-A | Preparation and application of isoxazoline derivative containing triazole thioether structure | 贵州大学 | 2026-05-19 | — | — | CN | disclosed |
| US-12606533-B2 | 3-phenylpropylamine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2026-04-21 | — | — | US | disclosed |
| US-20260070879-A1 | ISOXAZOLINE DERIVATIVES | ELANCO TIERGESUNDHEIT AG (CH) | 2026-03-12 | — | — | US | disclosed |
| US-12564193-B2 | Isoxazoline-substituted benzamide derivative, and preparation method therefor and use thereof | SHANDONG UNITED PESTICIDE INDUSTRY CO., LTD. (CN) | 2026-03-03 | — | — | US | disclosed |
| US-20250380697-A1 | ISOXAZOLINE DERIVATIVE COMPOUND AND INSECTICIDAL COMPOSITION COMPRISING SAME | KYUNG NONG CORPORATION (KR) | 2025-12-18 | — | — | US | disclosed |
| US-12497370-B2 | Isoxazoline derivatives | ELANCO TIERGESUNDHEIT AG (CH) | 2025-12-16 | — | — | US | disclosed |
| US-20250353824-A1 | 3-PHENYLPROPYLAMINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2025-11-20 | — | — | US | disclosed |
| WO-2025228900-A1 | ARYLAMIDE SUBSTITUTED INDAZOLES AND THE USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2025-11-06 | — | — | WO | disclosed |
| EP-4159732-B1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | SHANDONG UNITED PESTICIDE IND CO LTD (CN) | 2025-10-15 | — | — | EP | disclosed |
| CN-120004816-A | Isoxazoline derivatives | 礼蓝动物保健有限公司 | 2025-05-16 | — | — | CN | disclosed |
| US-4753962-A | HYPOGLYCEMIC, ANTIOBESITY AGENT | BEECHAM GROUP P.L.C. (GB) | 1988-06-28 | — | — | US | disclosed |
| US-4708441-A | LIQUID CRYSTALS | HOFFMAN-LA ROCHE INC. (US) | 1987-11-24 | — | — | US | disclosed |
| US-4704005-A | LIQUID CRYSTALS | HOFFMANN-LA ROCHE INC. (US) | 1987-11-03 | — | — | US | disclosed |
| US-4654371-A | ANTI-OBESITY, HYPOGLYCEMIA AGENTS | BEECHAM GROUP P.L.C. (GB) | 1987-03-31 | — | — | US | disclosed |
| US-4613208-A | ELECTROOPTICS; ULTRAVIOLET RADIATION STABILITY; QUICK RESPONSE | HOFFMANN-LA ROCHE INC. (US) | 1986-09-23 | — | — | US | disclosed |
| US-4595521-A | In liquid crystalline carrier | HOFFMANN-LA ROCHE INC. (US) | 1986-06-17 | — | — | US | disclosed |
| US-4550981-A | Liquid crystalline esters and mixtures | HOFFMANN-LA ROCHE INC. (US) | 1985-11-05 | — | — | US | disclosed |
| US-4478849-A | HYPERGLYCEMIC AGENTS | BEECHAM GROUP LIMITED (GB) | 1984-10-23 | — | — | US | disclosed |
| EP-0006735-B1 | SECONDARY AMINES, THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE | BEECHAM GROUP PLC (GB) | 1983-06-15 | — | — | EP | disclosed |
| EP-0006735-A1 | Secondary amines, their preparation, pharmaceutical compositions containing them and their use | BEECHAM GROUP PLC (GB) | 1980-01-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12564193-B2 | Isoxazoline-substituted benzamide derivative, and preparation method therefor and use thereof | CYP4F11, CYP4Z1, CYP4X1 | ALDH1A1 1874/4885HPGD 3387/4885MAPT 1682/4885 |
| US-20250353824-A1 | 3-PHENYLPROPYLAMINE DERIVATIVE | SF1, SF3A1, SFXN1 | ALDH1A1 358/4885HPGD 2153/4885MAPT 2719/4885 |
| US-12497370-B2 | Isoxazoline derivatives | CYP3A7, CYP4X1, CYP2A7 | ALDH1A1 906/4885HPGD 1527/4885MAPT 3165/4885 |
| US-20260070879-A1 | ISOXAZOLINE DERIVATIVES | CHRM1, CBR3, AFF1 | ALDH1A1 972/4885HPGD 3759/4885MAPT 4877/4885 |
| US-20250380697-A1 | ISOXAZOLINE DERIVATIVE COMPOUND AND INSECTICIDAL COMPOSITION COMPRISING SAME | VIP, CASP7, CYP4X1 | ALDH1A1 1181/4885HPGD 1764/4885MAPT 2451/4885 |
| US-12606533-B2 | 3-phenylpropylamine derivative | SF3A1, SF1, HTR1D | ALDH1A1 357/4885HPGD 3743/4885MAPT 4210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.