Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | HPGD | P15428 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL22799197 | 0.85 | CA1 (0.57) | ALDH1A1HPGDKDM4ECA1CA9 | |
| Phthalic Acid SCHEMBL31168189 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4ECA1CA9 | |
| Phthalic Acid SCHEMBL11042802 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4ECA1CA9 | |
| Phthalic Acid SCHEMBL28135993 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4ECA1CA9 | |
| Phenol SCHEMBL27429751 | 0.79 | CA1 (0.52) | ALDH1A1CA1CA9CA12CA2 | |
| Salicylic Acid SCHEMBL19066447 | 0.79 | ALDH1A1 (0.78) | ALDH1A1HPGDKDM4ECA1CA9 | |
| Salicylic Acid SCHEMBL28313591 | 0.78 | ALDH1A1 (0.95) | ALDH1A1HPGDKDM4ECA1CA9 | |
| Salicylic Acid SCHEMBL28222899 | 0.78 | ALDH1A1 (0.95) | ALDH1A1HPGDKDM4ECA1CA9 | |
| Phthalic Acid SCHEMBL1239767 | 0.78 | CA1 (0.48) | ALDH1A1HPGDKDM4ECA1CA9 | |
| Phthalic Acid SCHEMBL11604075 | 0.77 | ALDH1A1 (0.45) | ALDH1A1HPGDKDM4ECA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071667-A1 | ACRYLATE DERIVATIVES, ALCOHOL DERIVATIVES, AND METHOD FOR PRODUCING THEM | KURARAY CO., LTD. (JP) | 2012-03-22 | — | — | US | disclosed |
| US-20110117491-A1 | RESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN | TOKYO OHKA KOGYO CO., LTD. (JP) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071667-A1 | ACRYLATE DERIVATIVES, ALCOHOL DERIVATIVES, AND METHOD FOR PRODUCING THEM | ADH1A, ADH1C, ADH5 | ALDH1A1 122/4885HPGD 3325/4885KDM4E 2557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.