SCHEMBL7794852

SCHEMBL7794852

CCc1cc(CCC(=O)O)cc(C(C)(C)CC(C)(C)C)c1OC

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
THRA P10827 7/20 0.40
THRB P10828 7/20 0.40
FFAR4 Q5NUL3 5/20 0.36
POLB P06746 1/20 0.35
PPARD Q03181 1/20 0.35
PPARA Q07869 1/20 0.35
FFAR1 O14842 3/20 0.35
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
RXRG P48443 1/20 0.35
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7796410 0.90 THRA (0.39) THRATHRBFFAR4POLBPPARD
SCHEMBL7796625 0.87 GAA (0.39) THRATHRBFFAR4FFAR1RXRA
SCHEMBL7795934 0.87 THRB (0.39) THRATHRBRXRARXRBRXRG
SCHEMBL7792806 0.87 GAA (0.41) THRATHRBFFAR4POLBPPARD
SCHEMBL7794855 0.86 THRA (0.45) THRATHRBFFAR4FFAR1
SCHEMBL7796633 0.86 FFAR4 (0.41) THRATHRBFFAR4FFAR1RXRA
SCHEMBL6565884 0.85 MAPT (0.35) PPARA
SCHEMBL6565863 0.84 TNKS2 (0.39) PPARA
SCHEMBL7942500 0.83 KMT2A (0.37) KMT2A
SCHEMBL7942304 0.83 HSPA5 (0.41) THRATHRBFFAR4FFAR1RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed