SCHEMBL7796410

SCHEMBL7796410

CCc1cc(CCC(=O)O)cc(C(C)(C)CC)c1OC

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRA P10827 7/20 0.39
THRB P10828 7/20 0.39
RXRA P19793 2/20 0.38
RARG P13631 1/20 0.38
PPARG P37231 1/20 0.38
POLB P06746 1/20 0.37
PPARD Q03181 1/20 0.36
PPARA Q07869 1/20 0.36
FFAR1 O14842 3/20 0.36
RXRB P28702 1/20 0.36
RXRG P48443 1/20 0.36
FFAR4 Q5NUL3 3/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
LMNA P02545 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7794852 0.90 THRA (0.40) THRATHRBRXRAPOLBPPARD
SCHEMBL7792806 0.89 GAA (0.41) THRATHRBRXRAPOLBPPARD
SCHEMBL7792487 0.88 GAA (0.40) THRATHRBRXRARARGPPARG
SCHEMBL7792867 0.86 FFAR4 (0.41) THRATHRBRXRARARGPPARG
SCHEMBL7794855 0.86 THRA (0.45) THRATHRBFFAR1FFAR4LMNA
SCHEMBL7792544 0.86 THRB (0.40) THRATHRBRXRARARGPPARG
SCHEMBL6565760 0.85 MAPT (0.36) RXRARARGPPARGPPARA
SCHEMBL7942509 0.83 KMT2A (0.39) RXRARARGPPARGKMT2A
SCHEMBL6567746 0.82 TNKS2 (0.40) RXRARARGPPARGPPARA
SCHEMBL7796395 0.82 HSPA5 (0.43) THRATHRBRXRAFFAR1RXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed