Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.62 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.62 |
| ▸ | PGR | P06401 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.60 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | AR | P10275 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8331404 | 1.00 | CYP3A4 (0.62) | CYP3A4NR3C1HSD17B10HIF1APGR | |
| SCHEMBL6343098 | 0.87 | HIF1A (0.64) | CYP3A4NR3C1HSD17B10HIF1APGR | |
| SCHEMBL6563217 | 0.87 | HIF1A (0.64) | CYP3A4NR3C1HSD17B10HIF1APGR | |
| SCHEMBL7796323 | 0.86 | CYP3A4 (0.76) | CYP3A4NR3C1HSD17B10HIF1APGR | |
| SCHEMBL18351253 | 0.86 | CYP3A4 (0.76) | CYP3A4NR3C1HSD17B10HIF1APGR | |
| SCHEMBL7796325 | 0.86 | CYP3A4 (0.76) | CYP3A4NR3C1HSD17B10HIF1APGR | |
| SCHEMBL10602893 | 0.81 | LMNA (0.69) | CYP3A4NR3C1HSD17B10HIF1APGR | |
| SCHEMBL13768207 | 0.79 | PGR (0.53) | CYP3A4NR3C1HSD17B10HIF1APGR | |
| SCHEMBL13787664 | 0.79 | NR3C1 (0.55) | CYP3A4NR3C1HSD17B10HIF1APGR | |
| SCHEMBL20709748 | 0.79 | PGR (0.63) | CYP3A4NR3C1HSD17B10HIF1APGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941361-B1 | A METHOD FOR THE PREPARATION OF STEROID COMPOUNDS | DURAMED EUROP LTD (GB) | 2001-11-28 | — | — | EP | disclosed |
| EP-0941361-A1 | A METHOD FOR THE PREPARATION OF STEROID COMPOUNDS | Duramed Europe Limited (GB) | 1999-09-15 | — | — | EP | disclosed |
| WO-1998020151-A9 | A METHOD FOR THE PREPARATION OF STEROID COMPOUNDS | DURAMED EUROP LIMITED (GB) | 1999-06-17 | — | — | WO | disclosed |
| WO-1998020151-A1 | A METHOD FOR THE PREPARATION OF STEROID COMPOUNDS | DURAMED EUROPE LIMITED (GB) | 1998-05-14 | — | — | WO | disclosed |