SCHEMBL8433459

SCHEMBL8433459

CCOc1c(C)cc(C(C)(C)C)cc1CC(=O)OCCO

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.38
LMNA P02545 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
POLB P06746 2/20 0.34
GAA P10253 1/20 0.34
KMT2A Q03164 1/20 0.34
HSD17B10 Q99714 1/20 0.34
F2R P25116 2/20 0.34
RXRA P19793 2/20 0.33
PTGS2 P35354 2/20 0.33
RXRB P28702 1/20 0.33
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
HRH2 P25021 1/20 0.33
HRH1 P35367 1/20 0.33
RARG P13631 1/20 0.33
PPARG P37231 1/20 0.33
ELANE P08246 1/20 0.33
CD69 Q07108 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8433322 0.89 RXRA (0.43) MAPTLMNASMN1; SMN2POLBRXRA
SCHEMBL7941195 0.88 CYP4F2 (0.40) GAAKMT2AHSD17B10F2RPPARG
SCHEMBL8433317 0.87 PTGS2 (0.37) MAPTLMNASMN1; SMN2GAAKMT2A
SCHEMBL7933809 0.82 GAA (0.38) MAPTLMNASMN1; SMN2GAAKMT2A
SCHEMBL8430359 0.81 HSPA5 (0.36) SMN1; SMN2GAAKMT2AHSD17B10RXRA
SCHEMBL7794927 0.81 RXRA (0.50) SMN1; SMN2RXRARXRBALDH1A1RARG
SCHEMBL8434295 0.78 RXRA (0.37) RXRAPTGS2ALDH1A1RARGPPARG
SCHEMBL18050531 0.77 MAPT (0.40) MAPTLMNASMN1; SMN2POLBKMT2A
SCHEMBL7933544 0.77 RXRA (0.42) RXRARARGPPARGELANECD69
SCHEMBL18050494 0.77 ESR1 (0.36) MAPTLMNASMN1; SMN2KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5891939-A POLYMER STABILIZERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-04-06 US disclosed