Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7856801 | 0.85 | HCRTR1 (0.34) | NTRK1HCRTR2 | |
| SCHEMBL7785288 | 0.84 | GAA (0.35) | NTRK1 | |
| SCHEMBL7793925 | 0.82 | PRKCA (0.32) | — | |
| SCHEMBL7795321 | 0.79 | HTT (0.33) | HCRTR2 | |
| SCHEMBL7785295 | 0.78 | CYP3A4 (0.44) | NTRK1HCRTR2 | |
| SCHEMBL7791009 | 0.77 | NTRK1 (0.35) | NTRK1HCRTR2 | |
| SCHEMBL7795334 | 0.72 | KMO (0.36) | — | |
| SCHEMBL7867258 | 0.70 | ADRB2 (0.35) | — | |
| SCHEMBL7863555 | 0.68 | HTT (0.35) | HCRTR2 | |
| SCHEMBL7865023 | 0.68 | KDM4E (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435632-B1 | Phenylpyrimidine derivatives, process for preparing the same, liquid crystal compositions containing said derivatives as active ingredient, and liquid crystal elements using such compositions | SUMITOMO CHEMICAL CO (JP) | 2001-11-28 | — | — | EP | disclosed |
| EP-1067122-A2 | Phenylpyrimidine derivatives, process for preparing the same, liquid crystal compositions containing said derivatives as active ingredient, and liquid crystal elements using such compositions | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-10 | — | — | EP | disclosed |
| US-5723610-A | Alcohol reactants for forming phenylpyrimidine derivatives and process for preparing said alcohols | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-03-03 | — | — | US | disclosed |
| US-5539115-A | FERROELECTRIC CRYSTALS FOR OPTICAL APPARATUS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0435632-A2 | Phenylpyrimidine derivatives, process for preparing the same, liquid crystal compositions containing said derivatives as active ingredient, and liquid crystal elements using such compositions | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-07-03 | — | — | EP | disclosed |