Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793925 | 0.86 | PRKCA (0.32) | PRKCAHTT | |
| SCHEMBL7863562 | 0.82 | ADRB2 (0.46) | ADRB2ADRB1ADRB3LMNAALDH1A1 | |
| SCHEMBL7856801 | 0.80 | HCRTR1 (0.34) | ADRB2ADRB1ADRB3PRKCAALDH1A1 | |
| SCHEMBL7863558 | 0.80 | USP1 (0.34) | ADRB2ADRB1ADRB3PRKCALMNA | |
| SCHEMBL7856837 | 0.75 | CYP3A4 (0.54) | ADRB2ADRB1ADRB3LMNAALDH1A1 | |
| SCHEMBL7865025 | 0.74 | GABRA1 (0.41) | ADRB2ADRB1ADRB3LMNAALDH1A1 | |
| SCHEMBL8942949 | 0.70 | RXRA (0.51) | ADRB2ADRB1LMNAALDH1A1HTT | |
| SCHEMBL7795329 | 0.70 | NTRK1 (0.35) | — | |
| SCHEMBL1902239 | 0.70 | PTGDR2 (0.40) | PRKCAALDH1A1HTTMAPTMAPK1 | |
| SCHEMBL7863555 | 0.69 | HTT (0.35) | ADRB2ADRB1ADRB3LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067122-A2 | Phenylpyrimidine derivatives, process for preparing the same, liquid crystal compositions containing said derivatives as active ingredient, and liquid crystal elements using such compositions | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-10 | — | — | EP | disclosed |
| US-5723610-A | Alcohol reactants for forming phenylpyrimidine derivatives and process for preparing said alcohols | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-03-03 | — | — | US | disclosed |
| US-5539115-A | FERROELECTRIC CRYSTALS FOR OPTICAL APPARATUS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0435632-A2 | Phenylpyrimidine derivatives, process for preparing the same, liquid crystal compositions containing said derivatives as active ingredient, and liquid crystal elements using such compositions | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-07-03 | — | — | EP | disclosed |