Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1305632 | 0.89 | CES1 (0.40) | DNMT1HSP90AA1HSP90AB1CES1MEN1 | |
| SCHEMBL30616100 | 0.87 | DNMT1 (0.40) | DNMT1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL29368065 | 0.87 | DNMT1 (0.40) | DNMT1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL275907 | 0.87 | DNMT1 (0.40) | DNMT1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL8613188 | 0.87 | HSP90AA1 (0.44) | DNMT1HSP90AA1HSP90AB1CES1MEN1 | |
| SCHEMBL30436853 | 0.86 | DNMT1 (0.39) | DNMT1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL8595804 | 0.86 | DNMT1 (0.39) | DNMT1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL2949327 | 0.85 | DHFR (0.40) | DNMT1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL8418840 | 0.85 | WDR5 (0.37) | DNMT1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL12474165 | 0.85 | TYMP (0.39) | DNMT1HSP90AA1HSP90AB1MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0731105-B1 | Optically active tertiary phosphine compounds, transition metal complexes comprising the same as ligands and process for preparing optically active organic silicon compounds using said transition metal complexes | SUMITOMO CHEMICAL CO (JP) | 2001-12-05 | — | — | EP | disclosed |
| EP-0731105-A1 | Optically active tertiary phosphine compounds, transition metal complexes comprising the same as ligands and process for preparing optically active organic silicon compounds using said transition metal complexes | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-09-11 | — | — | EP | disclosed |