Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ADK | P55263 | 1/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5566890 | 0.97 | DHFR (0.38) | DHFRMAOAMAOBGSK3BADK | |
| SCHEMBL29176 | 0.89 | MAPT (0.39) | RAB9AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29361524 | 0.89 | MAPT (0.39) | RAB9AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5080119 | 0.88 | DHFR (0.40) | DHFRMAOAMAOBGSK3BADK | |
| SCHEMBL275907 | 0.87 | DNMT1 (0.40) | DHFRGSK3BADKDNMT1RAB9A | |
| SCHEMBL29368065 | 0.87 | DNMT1 (0.40) | DHFRGSK3BADKDNMT1RAB9A | |
| SCHEMBL30616100 | 0.87 | DNMT1 (0.40) | DHFRGSK3BADKDNMT1RAB9A | |
| SCHEMBL8961365 | 0.87 | DHFR (0.39) | DHFRMAOAMAOBGSK3BADK | |
| SCHEMBL430813 | 0.86 | GPR84 (0.35) | MAOAMAOBFLT3RAB9AALDH1A1 | |
| SCHEMBL8595804 | 0.86 | DNMT1 (0.39) | DHFRGSK3BADKDNMT1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111417618-B | Process for preparing enantiomerically and diastereomerically enriched cyclobutane amines and amides | 先正达参股股份有限公司 | 2023-06-30 | — | — | CN | claimed |
| CN-110312713-B | Process for preparing tetrahydrocarbazole carboxamide compounds | 百时美施贵宝公司 | 2022-08-12 | — | — | CN | claimed |
| CN-111217848-B | Spiro-dihydrobenzothiole diphenol compound, synthesis method and application thereof | 中国科学院上海有机化学研究所 | 2021-11-02 | — | — | CN | claimed |
| CN-111417618-A | Process for preparing enantiomerically and diastereomerically enriched cyclobutaneamines and cyclobutaneamides | 先正达参股股份有限公司 | 2020-07-14 | — | — | CN | claimed |
| CN-111217848-A | Spiro-dihydrobenzothiole diphenol compound, synthesis method and application thereof | 中国科学院上海有机化学研究所 | 2020-06-02 | — | — | CN | claimed |
| CN-111171068-A | Preparation method of silicon spiro-compound | 中国科学院上海有机化学研究所 | 2020-05-19 | — | — | CN | claimed |
| EP-1414783-B1 | METHOD FOR THE PRODUCTION OF AMINES BY REDUCTIVE AMINATION OF CARBONYL COMPOUNDS UNDER TRANSFER-HYDROGENATION CONDITIONS | EVONIK DEGUSSA GMBH (DE) | 2009-07-15 | — | — | EP | claimed |
| EP-0272787-B1 | CATALYTIC PRODUCTION OF OPTICALLY ACTIVE CARBOXYLIC ACID | Takasago International Corporation (JP) | 1992-05-06 | — | — | EP | claimed |
| JP-60199898-A | — | — | None | — | — | JP | disclosed |
| JP-61063690-A | — | — | None | — | — | JP | disclosed |
| CN-118043308-A | Bond formation method based on coupling reaction | 中外制药株式会社 | 2024-05-14 | — | — | CN | disclosed |
| CN-111556872-B | Synthesis of borate derivatives and uses thereof | 梅琳塔治疗公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-118005619-A | Process for producing heterocyclic compound | 武田药品工业株式会社 | 2024-05-10 | — | — | CN | disclosed |
| CN-111757874-B | Methods for preparing modulators of cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2024-03-08 | — | — | CN | disclosed |
| EP-0444930-B1 | Compounds containing 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl and catalytic metal complexes thereof | TAKASAGO PERFUMERY CO LTD (JP) | 1994-11-30 | — | — | EP | disclosed |
| EP-0385733-B1 | Process for preparing optically active 6-t-butoxy-3,5-dihydroxyhexanoic esters | TAKASAGO PERFUMERY CO LTD (JP) | 1994-06-01 | — | — | EP | disclosed |
| US-5144050-A | Hydrogenation Catalysts | MONSANTO COMPANY (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0444930-A1 | Compounds containing 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl and catalytic metal complexes thereof | Takasago International Corporation (JP) | 1991-09-04 | — | — | EP | disclosed |
| JP-S6163690-A | RUTHENIUM-PHOSPHINE COMPLEX | TAKASAGO CORP | 1986-04-01 | — | — | JP | disclosed |
| JP-S60199898-A | RHODIUM-PHOSPHINE COMPLEX | TAKASAGO CORP | 1985-10-09 | — | — | JP | disclosed |