SCHEMBL7796093

SCHEMBL7796093

c1ccc(-c2n[nH]c(-c3cccs3)n2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 6/20 0.62
NR1H3 Q13133 6/20 0.62
NPC1 O15118 4/20 0.53
RAB9A P51151 4/20 0.53
HPGDS O60760 1/20 0.53
LMNA P02545 1/20 0.53
DGAT1 O75907 1/20 0.53
HPGD P15428 4/20 0.53
CYP1A2 P05177 3/20 0.53
CYP3A4 P08684 3/20 0.53
CYP2C9 P11712 3/20 0.53
CYP2C19 P33261 3/20 0.53
MEN1 O00255 3/20 0.53
ALDH1A1 P00352 3/20 0.53
MAPT P10636 3/20 0.53
KMT2A Q03164 3/20 0.53
KDM4E B2RXH2 3/20 0.53
PPARG P37231 1/20 0.53
NCOA2 Q15596 1/20 0.53
NCOA1 Q15788 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17280143 0.89 ATR (0.50) NR1H2NR1H3NPC1RAB9AHPGD
SCHEMBL17570208 0.88 NR1H2 (0.60) NR1H2NR1H3NPC1RAB9AHPGDS
SCHEMBL22307745 0.81 NR1H2 (0.69) NR1H2NR1H3NPC1RAB9AHPGDS
SCHEMBL17336597 0.80 ALDH1A1 (0.62) NR1H2NR1H3NPC1RAB9ADGAT1
SCHEMBL666693 0.78 NR1H2 (1.00) NR1H2NR1H3NPC1RAB9AHPGDS
SCHEMBL17336593 0.77 HPGD (0.54) NR1H2NR1H3NPC1RAB9AHPGDS
SCHEMBL28681353 0.76 KDM4E (0.56) NPC1RAB9ALMNAHPGDCYP1A2
SCHEMBL26109969 0.76 NR1H2 (0.96) NR1H2NR1H3NPC1RAB9AHPGDS
SCHEMBL17574086 0.76 NR1H2 (0.96) NR1H2NR1H3NPC1RAB9AHPGDS
SCHEMBL1071190 0.76 NR1H2 (0.96) NR1H2NR1H3NPC1RAB9AHPGDS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180203175-A1 TRIAZOLE COMPOUND Konica Minolta, Inc. (JP) 2018-07-19 US disclosed
US-20180203175-A1 TRIAZOLE COMPOUND Konica Minolta, Inc. (JP) 2018-07-19 US disclosed
US-10012777-B2 Resin composition Konica Minolta, Inc. (JP) 2018-07-03 US disclosed
US-10012777-B2 Resin composition Konica Minolta, Inc. (JP) 2018-07-03 US disclosed
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE KONICA MINOLTA, INC (JP) 2015-11-26 US disclosed
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE KONICA MINOLTA, INC (JP) 2015-11-26 US disclosed
EP-0626077-B1 IMAGE-RECORDING MATERIALS POLAROID CORP (US) 2001-11-21 EP disclosed
EP-0803083-B1 IMAGE-RECORDING MATERIALS POLAROID CORP (US) 1999-04-21 EP disclosed
EP-0606465-B1 THERMALLY DEVELOPABLE PHOTOSENSITIVE MATERIAL POLAROID CORP (US) 1999-02-17 EP disclosed
EP-0607411-B1 THERMOGRAPHIC AND PHOTOTHERMOGRAPHIC IMAGING MATERIALS POLAROID CORP (US) 1998-10-14 EP disclosed
US-5340689-A For diffusion transfer color process POLAROID CORPORATION (US) 1994-08-23 US disclosed
EP-0607411-A1 THERMOGRAPHIC AND PHOTOTHERMOGRAPHIC IMAGING MATERIALS POLAROID CORPORATION (US) 1994-07-27 EP disclosed
EP-0606465-A1 THERMALLY DEVELOPABLE PHOTOSENSITIVE MATERIAL POLAROID CORPORATION (US) 1994-07-20 EP disclosed
US-5328799-A Multilayer heat and light sensitive element for color images POLAROID CORPORATION (US) 1994-07-12 US disclosed
WO-1994015257-A1 IMAGE-RECORDING MATERIALS POLAROID CORPORATION (US) 1994-07-07 WO disclosed
WO-1994015256-A1 IMAGE-RECORDING MATERIALS POLAROID CORPORATION (US) 1994-07-07 WO disclosed
US-5320929-A Cyclic 1,3-sulfur-nitrogen substituted color-providing material and at least one blaast group linked to each other through triazine group POLAROID CORPORATION (US) 1994-06-14 US disclosed
US-5316887-A Color-providing thiazolidine or tetrahydro-1,3-thiazine compounds, with reducing agent, thermal solvent, binder and silver halide POLAROID CORPORATION (US) 1994-05-31 US disclosed
WO-1994003833-A1 THERMOGRAPHIC AND PHOTOTHERMOGRAPHIC IMAGING MATERIALS POLAROID CORPORATION (US) 1994-02-17 WO disclosed
WO-1994003835-A1 THERMALLY DEVELOPABLE PHOTOSENSITIVE MATERIAL POLAROID CORPORATION (US) 1994-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE HRH3, HELZ, NBAS NR1H2 1059/4885NR1H3 766/4885NPC1 2503/4885
US-10012777-B2 Resin composition NBAS, WDR5, HRH3 NR1H2 1877/4885NR1H3 1458/4885NPC1 2768/4885
US-20180203175-A1 TRIAZOLE COMPOUND H1-10, TTI2, H1-2 NR1H2 534/4885NR1H3 787/4885NPC1 2718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.