SCHEMBL7796541

SCHEMBL7796541

COc1ccc(CCC(=O)O)cc1C1(C)CCCCC1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RARA P10276 2/20 0.53
RARB P10826 2/20 0.53
RARG P13631 2/20 0.53
PTGDR Q13258 1/20 0.51
PTGDR2 Q9Y5Y4 1/20 0.51
CYP26B1 Q9NR63 3/20 0.48
CYP26A1 O43174 2/20 0.48
FFAR1 O14842 5/20 0.45
FFAR4 Q5NUL3 5/20 0.45
RXRA P19793 2/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
PPARA Q07869 2/20 0.42
FFAR2 O15552 1/20 0.42
PPARD Q03181 1/20 0.42
CYP3A4 P08684 1/20 0.40
PLA2G4A P47712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7786595 0.87 RARA (0.55) RARARARBRARGPTGDRPTGDR2
SCHEMBL6566996 0.84 RARA (0.48) RARARARBRARGPTGDRPTGDR2
SCHEMBL7796128 0.84 CYP26B1 (0.52) RARARARBRARGPTGDRPTGDR2
SCHEMBL7944862 0.83 RARA (0.45) RARARARBRARGPTGDRPTGDR2
SCHEMBL6567017 0.82 RARA (0.46) RARARARBRARGPTGDRPTGDR2
SCHEMBL7683187 0.79 RARA (0.49) RARARARBRARGPTGDRPTGDR2
SCHEMBL7794944 0.79 THRA (0.41) RARARARBRARGPTGDRPTGDR2
SCHEMBL7796429 0.78 CYP26B1 (0.41) RARARARBRARGPTGDRPTGDR2
SCHEMBL7689383 0.77 RARB (0.77) RARARARBRARGPTGDRPTGDR2
Hydrochloric Acid SCHEMBL9738342 0.76 RARB (0.75) RARARARBRARGPTGDRPTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed