SCHEMBL7796540

SCHEMBL7796540

CCCOB(c1ccccc1)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.63
KMT2A Q03164 2/20 0.63
ALDH1A1 P00352 2/20 0.63
HPGD P15428 2/20 0.63
KDM4E B2RXH2 1/20 0.63
TRPM2 O94759 1/20 0.63
CYP1A2 P05177 1/20 0.63
CYP3A4 P08684 1/20 0.63
THRB P10828 1/20 0.63
ALOX15 P16050 1/20 0.63
TSHR P16473 1/20 0.63
ALOX12 P18054 1/20 0.63
MAPK1 P28482 1/20 0.63
TDP1 Q9NUW8 1/20 0.63
LYPLA1 O75608 1/20 0.49
LYPLA2 O95372 1/20 0.49
ORAI1 Q96D31 2/20 0.48
ORAI2 Q96SN7 2/20 0.48
ORAI3 Q9BRQ5 2/20 0.48
TRPV6 Q9H1D0 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7799309 0.87 TSHR (0.59) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL3279116 0.84 TRPV6 (0.50) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL7796509 0.82 MEN1 (0.42) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL7800329 0.81 TSHR (0.56) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL1275435 0.78 PCSK9 (0.47) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL341835 0.77 KDM4E (1.00) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL18782421 0.77 KDM4E (0.57) MEN1KMT2AALDH1A1HPGDKDM4E
Water SCHEMBL27746937 0.77 ALDH1A1 (0.38) MEN1KMT2AALDH1A1HPGDKDM4E
Water SCHEMBL27688377 0.77 ALDH1A1 (0.38) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL2412888 0.76 KDM4E (0.96) MEN1KMT2AALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112020520-B Method for producing allyl monomer copolymer having polar group 国立大学法人东京大学 2023-03-10 CN disclosed
EP-0808849-B1 Process for the production of ethylenic polymers SHOWA DENKO KK (JP) 2001-12-19 EP disclosed
US-6011127-A CATALYST COMPRISING A CHROMIUM COMPOUND, AN ALUMOXANE AND AN ORGANOMETALLIC ALKOXIDE AND/OR ORGANOMETALLIC SILOXIDE AND A CARRIER SUPPORTING THEREON THESE COMPOUNDS. SHOWA DENKO K.K. (JP) 2000-01-04 US disclosed
EP-0808849-A1 Process for the production of ethylenic polymers SHOWA DENKO KABUSHIKI KAISHA (JP) 1997-11-26 EP disclosed