Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | LYPLA1 | O75608 | 1/20 | 0.46 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.46 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.44 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796540 | 0.87 | MEN1 (0.63) | TSHRALDH1A1TDP1CYP3A4MAPK1 | |
| SCHEMBL3289446 | 0.83 | PCSK9 (0.52) | TSHRALDH1A1TDP1CYP3A4MAPK1 | |
| SCHEMBL10406540 | 0.82 | ALDH1A1 (0.38) | TSHRALDH1A1TDP1CYP3A4MAPK1 | |
| SCHEMBL1128562 | 0.80 | PCSK9 (0.58) | TSHRALDH1A1TDP1CYP3A4MAPK1 | |
| Phosphine SCHEMBL28357175 | 0.79 | PCSK9 (0.56) | TSHRALDH1A1TDP1CYP3A4MAPK1 | |
| SCHEMBL7800329 | 0.78 | TSHR (0.56) | TSHRALDH1A1TDP1CYP3A4MAPK1 | |
| SCHEMBL11711998 | 0.76 | PCSK9 (0.48) | TSHRALDH1A1CYP3A4MAPK1MEN1 | |
| SCHEMBL30545064 | 0.76 | PCSK9 (0.48) | TSHRALDH1A1CYP3A4MAPK1MEN1 | |
| SCHEMBL30545060 | 0.76 | PCSK9 (0.48) | TSHRALDH1A1CYP3A4MAPK1MEN1 | |
| SCHEMBL12266395 | 0.75 | LYPLA1 (0.44) | TSHRALDH1A1TDP1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808849-B1 | Process for the production of ethylenic polymers | SHOWA DENKO KK (JP) | 2001-12-19 | — | — | EP | disclosed |
| US-6011127-A | CATALYST COMPRISING A CHROMIUM COMPOUND, AN ALUMOXANE AND AN ORGANOMETALLIC ALKOXIDE AND/OR ORGANOMETALLIC SILOXIDE AND A CARRIER SUPPORTING THEREON THESE COMPOUNDS. | SHOWA DENKO K.K. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0624315-B1 | Diaryl(pyridinio and isoquinolinio) boron fungicidal agents | AMERICAN CYANAMID CO (US) | 1998-07-01 | — | — | EP | disclosed |
| EP-0808849-A1 | Process for the production of ethylenic polymers | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1997-11-26 | — | — | EP | disclosed |
| EP-0519496-B1 | Thermosetting copolymers, silicon carbide-based fiber and processes for producing same | TONEN CORP (JP) | 1996-05-22 | — | — | EP | disclosed |
| EP-0404503-B1 | Boron-containing, silicon nitride-based ceramic shaped body production process | TONEN CORP (JP) | 1996-03-06 | — | — | EP | disclosed |
| EP-0389084-B1 | Process for producing a polyborosilazane | TONEN CORP (JP) | 1995-09-20 | — | — | EP | disclosed |
| EP-0624315-A1 | Diaryl(pyridinio and isoquinolinio) boron fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-11-17 | — | — | EP | disclosed |
| US-5354740-A | For phytopathogenic fungi | AMERICAN CYANAMID COMPANY (US) | 1994-10-11 | — | — | US | disclosed |
| US-5354741-A | Diaryl (pyridinio and isoquinolinio) boron insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-10-11 | — | — | US | disclosed |
| US-5292830-A | Silane, silazane, boron block crosslinked copolymers | TONEN CORPORATION (JP) | 1994-03-08 | — | — | US | disclosed |
| EP-0519496-A1 | Thermosetting copolymers, silicon carbide-based fiber and processes for producing same | Tonen Corporation (JP) | 1992-12-23 | — | — | EP | disclosed |
| US-5128286-A | BORON-CONTAINING, SILICON NITRIDE-BASED CERAMIC SHAPED BODY | TONEN CORPORATION (JP) | 1992-07-07 | — | — | US | disclosed |
| US-5030744-A | Polyborosilazane and process for producing same | TONEN CORPORATION (JP) | 1991-07-09 | — | — | US | disclosed |
| EP-0404503-A1 | Boron-containing, silicon nitride-based ceramic shaped body production process | Tonen Corporation (JP) | 1990-12-27 | — | — | EP | disclosed |
| EP-0389084-A2 | Process for producing a polyborosilazane | Tonen Corporation (JP) | 1990-09-26 | — | — | EP | disclosed |