Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 3/20 | 0.45 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13937943 | 1.00 | TDP1 (0.58) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL7797911 | 1.00 | TDP1 (0.58) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL7284629 | 0.85 | ALDH1A1 (0.61) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL7829080 | 0.85 | ALDH1A1 (0.61) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL8075909 | 0.85 | ALDH1A1 (0.61) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL1274991 | 0.81 | TDP1 (0.48) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL7800089 | 0.81 | GSK3A (0.44) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL16558903 | 0.81 | CASP3 (0.46) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL12197537 | 0.81 | CASP3 (0.46) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL7789570 | 0.80 | ALDH1A1 (0.55) | TDP1ALDH1A1GAAPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482478-B2 | Diastereoselective epoxidation of allylically substituted alkenes using metalloporphyrin catalysts | THE UNIVERSITY OF HONG KONG (CN) | 2009-01-27 | — | — | US | disclosed |
| US-7482478-B2 | Diastereoselective epoxidation of allylically substituted alkenes using metalloporphyrin catalysts | THE UNIVERSITY OF HONG KONG (CN) | 2009-01-27 | — | — | US | disclosed |
| EP-0748801-B1 | 2-ISOXAZOLINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING RELATED DERIVATIVES FROM THE SAME | DAICEL CHEM (JP) | 2001-12-19 | — | — | EP | disclosed |
| US-6018069-A | 2-isoxazoline derivative and process for producing the same and process for producing related derivatives from the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| US-5994558-A | 2-isoxazoline derivative and process for producing the same; and process for producing related derivatives from the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| US-5962692-A | 2-isoxazoline derivative and process for producing the same, and process for producing related derivatives from the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5750717-A | 2-isoxazoline derivative and process for producing the same, and process for producing related derivatives from the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0748801-A1 | 2-ISOXAZOLINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING RELATED DERIVATIVES FROM THE SAME | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-18 | — | — | EP | disclosed |