Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 5/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7139233 | 0.91 | CTSK (0.41) | CTSK | |
| SCHEMBL7132057 | 0.82 | HDAC3 (0.37) | — | |
| SCHEMBL7132836 | 0.81 | SIRT2 (0.44) | CTSS | |
| SCHEMBL7799740 | 0.76 | SYK (0.47) | SYKCTSKCTSSPPARA | |
| SCHEMBL7797006 | 0.76 | L3MBTL1 (0.45) | CTSKL3MBTL1 | |
| SCHEMBL7139316 | 0.76 | NAMPT (0.40) | CTSKL3MBTL1 | |
| SCHEMBL7139673 | 0.73 | CTSK (0.35) | CTSK | |
| SCHEMBL18085404 | 0.70 | SYK (0.60) | SYKL3MBTL1 | |
| SCHEMBL24365709 | 0.69 | SYK (0.49) | SYKCTSKCTSSPPARA | |
| SCHEMBL2736627 | 0.69 | ATM (0.56) | SYKCTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159260-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000055124-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |