Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7132828 | 0.79 | ALDH1A1 (0.39) | L3MBTL1 | |
| SCHEMBL7796787 | 0.78 | L3MBTL1 (0.40) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL7799736 | 0.77 | L3MBTL1 (0.40) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL7797009 | 0.76 | SYK (0.45) | L3MBTL1CTSK | |
| SCHEMBL7138159 | 0.71 | CCR6 (0.38) | L3MBTL1 | |
| SCHEMBL25801927 | 0.71 | L3MBTL1 (0.63) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL8899583 | 0.70 | L3MBTL1 (0.76) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL7137846 | 0.69 | L3MBTL1 (0.39) | L3MBTL1CTSK | |
| SCHEMBL30483146 | 0.69 | L3MBTL1 (0.43) | L3MBTL1NPSR1 | |
| SCHEMBL9781776 | 0.69 | L3MBTL1 (0.78) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159260-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000055124-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |