Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 4/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7139680 | 0.89 | CTSS (0.43) | CTSKCTSSMEN1KMT2ALMNA | |
| SCHEMBL7137802 | 0.81 | CTSK (0.44) | CTSKCTSSCTSLCTSBREN | |
| SCHEMBL7139684 | 0.81 | CTSS (0.49) | CTSKCTSSMEN1KMT2ALMNA | |
| SCHEMBL7137259 | 0.81 | CTSD (0.57) | CTSKCTSSKMT2ACTSLCTSB | |
| SCHEMBL7137824 | 0.80 | CTSK (0.48) | CTSKCTSSMEN1KMT2ALMNA | |
| SCHEMBL7131848 | 0.80 | MEN1 (0.50) | CTSSMEN1KMT2ALMNACTSL | |
| SCHEMBL7134710 | 0.79 | CTSK (0.45) | CTSKCTSSCA2CTSDREN | |
| SCHEMBL7139828 | 0.78 | CTSK (0.46) | CTSKCTSSMEN1KMT2ALMNA | |
| SCHEMBL7138049 | 0.78 | HPGD (0.53) | CTSSMEN1KMT2ALMNACTSL | |
| SCHEMBL7139401 | 0.78 | CCR1 (0.46) | CTSSMEN1KMT2ALMNACTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159260-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000055124-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |