SCHEMBL7797155

SCHEMBL7797155

Fc1cc(Br)cc(F)c1OC(F)(F)C(F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MAPT P10636 2/20 0.34
RECQL P46063 1/20 0.33
MEN1 O00255 1/20 0.32
USP2 O75604 1/20 0.32
ALOX15 P16050 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7760349 0.81 ALDH1A1 (0.40) ALDH1A1TSHRHSD17B10MAPTRECQL
SCHEMBL7911138 0.77 RECQL (0.42) ALDH1A1TSHRHSD17B10MAPTRECQL
SCHEMBL28819149 0.76 MAPT (0.36) MAPTKMT2A
SCHEMBL6558034 0.76 MAPT (0.36) MAPTKMT2A
SCHEMBL9013332 0.74 MAPT (0.35) MAPT
SCHEMBL9501334 0.74 ALDH1A1 (0.34) ALDH1A1TSHRHSD17B10MAPTRECQL
SCHEMBL9804244 0.72 MAPT (0.34) MAPT
SCHEMBL7767195 0.72 MAPT (0.41) MAPTKMT2A
SCHEMBL17961012 0.71 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10RECQL
SCHEMBL7913730 0.70 CYP2C9 (0.36) ALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010019121-A1 PHENYL POLYHALOALKYL ETHER DERIVATIVES, LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME, AND LIQUID-CRYSTAL DISPLAY ELEMENT SHIBATA KOUICHI (JP) 2001-09-06 US disclosed
EP-0945422-A1 PHENYL POLYHALOALKYL ETHER DERIVATIVES, LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME, AND LIQUID-CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1999-09-29 EP disclosed