Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL918875 | 0.82 | — | — | |
| SCHEMBL17066828 | 0.74 | PPARG (0.32) | PPARGPPARDPPARA | |
| SCHEMBL17468172 | 0.71 | — | — | |
| SCHEMBL3141803 | 0.65 | — | — | |
| SCHEMBL401757 | 0.65 | — | — | |
| SCHEMBL28586110 | 0.65 | — | — | |
| SCHEMBL6577421 | 0.64 | — | — | |
| SCHEMBL17441373 | 0.64 | — | — | |
| SCHEMBL3145832 | 0.64 | ALDH1A1 (0.33) | PPARGPPARDPPARA | |
| SCHEMBL12084338 | 0.64 | LMNA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004753-B1 | PREPARATION OF TETRAHYDROBENZOXOCINS AND CIS-HEXAHYDRODIBENZOPYRANONES | ELI LILLY AND COMPANY (US) | 1982-05-26 | — | — | EP | claimed |
| EP-0004753-A1 | Preparation of tetrahydrobenzoxocins and cis-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1979-10-17 | — | — | EP | claimed |
| US-4171315-A | Preparation of cis-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1979-10-16 | — | — | US | claimed |
| US-4133816-A | Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones and intermediates therefor | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | claimed |
| US-4115403-A | Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo [b,d]pyran-9-ones and intermediates therefor | ELI LILLY AND COMPANY (US) | 1978-09-19 | — | — | US | claimed |
| US-4054581-A | Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones and intermediates therefor | ELI LILLY AND COMPANY (US) | 1977-10-18 | — | — | US | claimed |
| US-20100298579-A1 | Process for preparing synthetic cannabinoids | THC PHARM GMBH (DE) | 2010-11-25 | — | — | US | disclosed |
| US-20100298579-A1 | Process for preparing synthetic cannabinoids | THC PHARM GMBH (DE) | 2010-11-25 | — | — | US | disclosed |
| US-4599327-A | NONHABIT-FORMING ANALGESICS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) | 1986-07-08 | — | — | US | disclosed |
| EP-0004753-B1 | PREPARATION OF TETRAHYDROBENZOXOCINS AND CIS-HEXAHYDRODIBENZOPYRANONES | ELI LILLY AND COMPANY (US) | 1982-05-26 | — | — | EP | disclosed |
| EP-0004753-A1 | Preparation of tetrahydrobenzoxocins and cis-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1979-10-17 | — | — | EP | disclosed |
| EP-0004753-A1 | Preparation of tetrahydrobenzoxocins and cis-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1979-10-17 | — | — | EP | disclosed |
| US-4171315-A | Preparation of cis-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1979-10-16 | — | — | US | disclosed |
| US-4171315-A | Preparation of cis-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1979-10-16 | — | — | US | disclosed |
| US-4133816-A | Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones and intermediates therefor | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
| US-4115403-A | Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo [b,d]pyran-9-ones and intermediates therefor | ELI LILLY AND COMPANY (US) | 1978-09-19 | — | — | US | disclosed |
| US-4115403-A | Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo [b,d]pyran-9-ones and intermediates therefor | ELI LILLY AND COMPANY (US) | 1978-09-19 | — | — | US | disclosed |
| US-4054581-A | Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones and intermediates therefor | ELI LILLY AND COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
| US-4054581-A | Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones and intermediates therefor | ELI LILLY AND COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298579-A1 | Process for preparing synthetic cannabinoids | CNR2, CNR1, FAAH | PPARG 657/4885PPARD 202/4885PPARA 637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.