SCHEMBL7797385

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14769945	0.88	GSK3B (0.47)	DRD2ACACBCACNA1HCKS1BSKP1
	SCHEMBL7803943	0.85	DRD2 (0.43)	DRD2ACACBCACNA1HCKS1BSKP1
	SCHEMBL7390208	0.81	HTR4 (0.43)	DRD2ACACBCACNA1HCKS1BSKP1
	SCHEMBL1428801	0.81	KDM1A (0.46)	CACNA1HKCNH2CACNA1ICYP2D6KDM1A
	SCHEMBL28037376	0.80	DRD2 (0.50)	DRD2ACACBCACNA1HCKS1BSKP1
	SCHEMBL7804764	0.79	DRD2 (0.49)	DRD2ACACBCKS1BSKP1SKP2
	SCHEMBL13965728	0.79	CACNA1I (0.56)	DRD2CACNA1HCKS1BSKP1SKP2
	SCHEMBL22544222	0.78	CACNA1I (0.52)	DRD2ACACBCKS1BSKP1SKP2
	SCHEMBL4419844	0.78	DRD2 (0.48)	DRD2ACACBCKS1BSKP1SKP2
	SCHEMBL4419840	0.78	DRD2 (0.48)	DRD2CKS1BSKP1SKP2KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.