Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.53 |
| ▸ | NOS2 | P35228 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12963699 | 0.82 | NOS3 (0.55) | NOS3NOS2SMN1; SMN2TLR8ALDH1A1 | |
| SCHEMBL15286809 | 0.81 | SMN1; SMN2 (0.43) | NOS3NOS2SMN1; SMN2TLR8NPY1R | |
| SCHEMBL23482212 | 0.81 | GAA (0.56) | NOS3NOS2TLR8ALDH1A1MEN1 | |
| SCHEMBL9313985 | 0.79 | TLR8 (0.65) | NOS3NOS2SMN1; SMN2TLR8ALDH1A1 | |
| SCHEMBL15286764 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2TLR8NPY1RSYKKARS1 | |
| SCHEMBL15286470 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2TLR8SYKALDH1A1MEN1 | |
| SCHEMBL11187910 | 0.78 | DNM2 (0.55) | NOS3NOS2TLR8ALDH1A1NOS1 | |
| SCHEMBL24672584 | 0.78 | TLR8 (0.58) | NOS3NOS2SMN1; SMN2TLR8ALDH1A1 | |
| SCHEMBL9884955 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2TLR8NPY1RSYKALDH1A1 | |
| SCHEMBL8345724 | 0.78 | NOS3 (0.59) | NOS3NOS2SMN1; SMN2TLR8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0796847-B1 | Pyridine derivative, anti-ulcer drug, and antibacterial drug | SHISEIDO CO LTD (JP) | 2001-11-28 | — | — | EP | disclosed |
| US-6017937-A | BACTERICIDE AGAINST HELICOBACTER PYROLI; INHIBITING ACID SECRETION IN STOMACH OF MAN OR MAMMALS, PREVENTING OR CURING ULCER | SHISEIDO CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| US-5859032-A | HAVING ANTIBACTERIAL ACTIVITY AGAINST HELICOBACTER PYLORI | SHISEIDO CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0796847-A1 | Pyridine derivative, anti-ulcer drug, and antibacterial drug | SHISEIDO COMPANY LIMITED (JP) | 1997-09-24 | — | — | EP | disclosed |