Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NOS3 | P29474 | 1/20 | 0.52 |
| ▸ | NOS2 | P35228 | 1/20 | 0.52 |
| ▸ | DNM2 | P50570 | 7/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24672584 | 0.95 | TLR8 (0.58) | TLR8ALDH1A1MAPK1TP53LMNA | |
| SCHEMBL8543215 | 0.93 | DNM2 (0.57) | TLR8ALDH1A1MAPK1TP53LMNA | |
| SCHEMBL13989410 | 0.90 | TLR8 (0.61) | TLR8ALDH1A1MAPK1TP53LMNA | |
| SCHEMBL12963699 | 0.89 | NOS3 (0.55) | TLR8ALDH1A1MAPK1TP53LMNA | |
| SCHEMBL8345724 | 0.80 | NOS3 (0.59) | TLR8ALDH1A1MAPK1TP53LMNA | |
| SCHEMBL16608857 | 0.80 | ALDH1A1 (0.73) | TLR8ALDH1A1MAPK1TP53LMNA | |
| SCHEMBL13989429 | 0.80 | TLR8 (0.50) | TLR8ALDH1A1MAPK1TP53LMNA | |
| SCHEMBL11446300 | 0.80 | NOS3 (0.46) | TLR8ALDH1A1MAPK1TP53LMNA | |
| SCHEMBL11454656 | 0.80 | DNM2 (0.55) | TLR8ALDH1A1MAPK1NOS3NOS2 | |
| SCHEMBL23482212 | 0.79 | GAA (0.56) | TLR8ALDH1A1MAPK1TP53NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5315017-A | Peroxidation and eicosanoid biosynthesis inhibition | ADIR ET COMPAGNIE (FR) | 1994-05-24 | — | — | US | disclosed |
| EP-0512899-A1 | Benzopyran compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-11-11 | — | — | EP | disclosed |