Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 6/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14687535 | 0.89 | HSD17B10 (0.39) | ALDH1A1HSD17B10HPGDCYP1A2THRB | |
| SCHEMBL2344564 | 0.82 | GPR84 (0.40) | ALDH1A1HSD17B10HPGDTSHRMAPK1 | |
| SCHEMBL29368065 | 0.82 | DNMT1 (0.40) | ALDH1A1HSD17B10HPGDTSHRMAPK1 | |
| SCHEMBL30616100 | 0.82 | DNMT1 (0.40) | ALDH1A1HSD17B10HPGDTSHRMAPK1 | |
| SCHEMBL275907 | 0.82 | DNMT1 (0.40) | ALDH1A1HSD17B10HPGDTSHRMAPK1 | |
| SCHEMBL8595804 | 0.81 | DNMT1 (0.39) | ALDH1A1HSD17B10HPGDTSHRMAPK1 | |
| SCHEMBL30436853 | 0.81 | DNMT1 (0.39) | ALDH1A1HSD17B10HPGDTSHRMAPK1 | |
| SCHEMBL7799304 | 0.80 | MAPT (0.53) | ALDH1A1HPGDCYP1A2CYP3A4MAPT | |
| SCHEMBL146878 | 0.79 | ALDH1A1 (0.44) | ALDH1A1HSD17B10CYP1A2TSHRMAPK1 | |
| SCHEMBL5107 | 0.79 | ALDH1A1 (0.44) | ALDH1A1HSD17B10CYP1A2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8245662-A | — | — | None | — | — | JP | disclosed |
| EP-0731105-B1 | Optically active tertiary phosphine compounds, transition metal complexes comprising the same as ligands and process for preparing optically active organic silicon compounds using said transition metal complexes | SUMITOMO CHEMICAL CO (JP) | 2001-12-05 | — | — | EP | disclosed |
| US-5621129-A | Optically active tertiary phosphine compound, transition metal complex comprising the same as ligand and process for preparing optically active organic silicon compound using said transition metal complex | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| JP-H08245662-A | TERTIARY PHOSPHINE COMPOUND, TRANSITION METAL COMPLEX CONTAINING THE COMPOUND AS LIGHAND AND ITS USE | SUMITOMO CHEM CO LTD | 1996-09-24 | — | — | JP | disclosed |
| EP-0731105-A1 | Optically active tertiary phosphine compounds, transition metal complexes comprising the same as ligands and process for preparing optically active organic silicon compounds using said transition metal complexes | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-09-11 | — | — | EP | disclosed |