Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29496547 | 0.87 | MAPT (0.67) | MAPTKDM4EHPGDKMT2AMEN1 | |
| SCHEMBL1606348 | 0.87 | MAPT (0.67) | MAPTKDM4EHPGDKMT2AMEN1 | |
| SCHEMBL29834220 | 0.87 | MAPT (0.67) | MAPTKDM4EHPGDKMT2AMEN1 | |
| SCHEMBL14687535 | 0.87 | HSD17B10 (0.39) | MAPTHPGDALDH1A1RAB9ANQO1 | |
| SCHEMBL12446367 | 0.82 | MAPT (0.54) | MAPTKDM4EHPGDKMT2AMEN1 | |
| SCHEMBL7797543 | 0.80 | ALDH1A1 (0.37) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL24779254 | 0.77 | MAPT (0.51) | MAPTKDM4EHPGDKMT2AMEN1 | |
| SCHEMBL7809875 | 0.77 | MAPT (0.47) | MAPTKDM4EHPGDKMT2AMEN1 | |
| SCHEMBL7804747 | 0.77 | MAPT (0.59) | MAPTKDM4EHPGDKMT2AMEN1 | |
| SCHEMBL5107 | 0.75 | ALDH1A1 (0.44) | MAPTKDM4EALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7149776-A | — | — | None | — | — | JP | disclosed |
| EP-0647647-B1 | Tertiary phosphine compound and transition metal complex comprising the same as ligand | SUMITOMO CHEMICAL CO (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5523437-A | Tertiary phosphine compound and transition metal complex comprising the same as ligand | SUMITOMO CHEMICAL CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| JP-H07149776-A | OPTICALLY ACTIVE TERTIARY PHOSPHINE COMPOUND, TRANSITION METAL COMPLEX CONTAINING THE SAME AS LIGAND AND ITS USE | SUMITOMO CHEM CO LTD | 1995-06-13 | — | — | JP | disclosed |
| EP-0647647-A1 | Tertiary phosphine compound and transition metal complex comprising the same as ligand | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-04-12 | — | — | EP | disclosed |