Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490658 | 0.89 | ALOX5 (0.49) | ALOX5NR1H4PTGDR2LTB4RLTB4R2 | |
| SCHEMBL6502665 | 0.89 | ALOX5 (0.49) | ALOX5NR1H4PTGDR2LTB4RLTB4R2 | |
| SCHEMBL8370953 | 0.86 | SMN1; SMN2 (0.44) | LMNAALDH1A1MEN1NPC1KMT2A | |
| SCHEMBL6490606 | 0.81 | ALOX5 (0.54) | ALOX5L3MBTL1PTGDR2LTB4RLTB4R2 | |
| SCHEMBL6490808 | 0.80 | RAB9A (0.53) | ALOX5NR1H4L3MBTL1LMNALTB4R | |
| SCHEMBL6490812 | 0.80 | RAB9A (0.53) | ALOX5NR1H4L3MBTL1LMNALTB4R | |
| SCHEMBL7803604 | 0.80 | MMP13 (0.43) | ALOX5NR1H4L3MBTL1LMNAPTGDR2 | |
| SCHEMBL16134420 | 0.78 | MEN1 (0.43) | NR1H4L3MBTL1LMNALTB4RLTB4R2 | |
| SCHEMBL16134436 | 0.77 | MEN1 (0.43) | NR1H4ALDH1A1MEN1KMT2AMAOB | |
| SCHEMBL12894591 | 0.73 | NR1H4 (0.58) | ALOX5NR1H4L3MBTL1LMNALTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1236767-C | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 2006-01-18 | — | — | CN | disclosed |
| US-6881736-B1 | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-19 | — | — | US | disclosed |
| CN-1377269-A | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 2002-10-30 | — | — | CN | disclosed |