Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6489697 | 0.89 | LTA4H (0.44) | MMP13ALOX5LTA4HEPHX2LTB4R | |
| SCHEMBL6489689 | 0.89 | LTA4H (0.44) | MMP13ALOX5LTA4HEPHX2LTB4R | |
| SCHEMBL6491209 | 0.82 | LTA4H (0.48) | MMP13ALOX5LTA4HEPHX2LTB4R | |
| SCHEMBL7797646 | 0.80 | ALOX5 (0.48) | ALOX5NR1H4LMNAL3MBTL1LTB4R | |
| SCHEMBL6178942 | 0.78 | ALOX5 (0.47) | ALOX5NR1H4LMNALTB4RLTB4R2 | |
| SCHEMBL6178946 | 0.78 | ALOX5 (0.47) | ALOX5NR1H4LMNALTB4RLTB4R2 | |
| SCHEMBL6490808 | 0.73 | RAB9A (0.53) | MMP13ALOX5NR1H4LMNAL3MBTL1 | |
| SCHEMBL6490812 | 0.73 | RAB9A (0.53) | MMP13ALOX5NR1H4LMNAL3MBTL1 | |
| SCHEMBL6176932 | 0.72 | ALOX5 (0.52) | ALOX5NR1H4LMNALTB4RLTB4R2 | |
| SCHEMBL27533969 | 0.71 | PPARA (0.47) | ALOX5LTA4HEPHX2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881736-B1 | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-19 | — | — | US | disclosed |