Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797724 | 1.00 | LMNA (0.60) | LMNASMN1; SMN2TSHRMAPK1TP53 | |
| Hydrochloric Acid SCHEMBL377316 | 0.98 | LMNA (0.59) | LMNASMN1; SMN2TSHRMAPK1TP53 | |
| SCHEMBL11712248 | 0.85 | LMNA (0.58) | LMNASMN1; SMN2TSHRMAPK1 | |
| SCHEMBL31409203 | 0.84 | LMNA (0.90) | LMNASMN1; SMN2TSHRMAPK1 | |
| SCHEMBL377315 | 0.84 | LMNA (0.59) | LMNASMN1; SMN2 | |
| SCHEMBL7046446 | 0.84 | LMNA (0.63) | LMNASMN1; SMN2 | |
| SCHEMBL28309840 | 0.84 | LMNA (0.63) | LMNASMN1; SMN2 | |
| SCHEMBL17343608 | 0.82 | LMNA (0.66) | LMNASMN1; SMN2 | |
| SCHEMBL7581409 | 0.78 | LMNA (0.42) | LMNASMN1; SMN2TSHRMAPK1 | |
| SCHEMBL7581413 | 0.78 | LMNA (0.42) | LMNASMN1; SMN2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4364921-A | RADIOPACITY | SCHERING, AKTIENGESELLSCHAFT (DE) | 1982-12-21 | — | — | US | claimed |
| EP-0851854-B1 | PROCESS FOR THE PURIFICATION OF AN INTERMEDIATE IN THE PREPARATION OF IOPAMIDOL | BRACCO IMAGING SPA (IT) | 2001-12-12 | — | — | EP | disclosed |
| US-5849953-A | Process for the purification of an intermediate | FRUCTAMINE S.P.A. (IT) | 1998-12-15 | — | — | US | disclosed |
| EP-0571593-B1 | NEW NON IONIC IODIZED AGENTS FOR X-RAY CONTRASTING, METHOD FOR PREPARING THEM AND GALENICAL COMPOSITIONS CONTAINING THEM | INVEST JUSTESA IMAGEN S A CENT (ES) | 1996-10-30 | — | — | EP | disclosed |
| US-4364921-A | RADIOPACITY | SCHERING, AKTIENGESELLSCHAFT (DE) | 1982-12-21 | — | — | US | disclosed |