Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28309840 | 1.00 | LMNA (0.63) | LMNASMN1; SMN2MEN1KMT2AHSD17B10 | |
| SCHEMBL7709204 | 0.86 | LMNA (0.90) | LMNASMN1; SMN2 | |
| SCHEMBL28451566 | 0.85 | LMNA (0.55) | LMNASMN1; SMN2 | |
| SCHEMBL7075563 | 0.85 | LMNA (0.55) | LMNASMN1; SMN2 | |
| SCHEMBL7797724 | 0.84 | LMNA (0.60) | LMNASMN1; SMN2 | |
| SCHEMBL7797725 | 0.84 | LMNA (0.60) | LMNASMN1; SMN2 | |
| SCHEMBL9171058 | 0.83 | LMNA (0.53) | LMNASMN1; SMN2 | |
| SCHEMBL8622218 | 0.83 | LMNA (0.50) | LMNA | |
| SCHEMBL377315 | 0.82 | LMNA (0.59) | LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL377316 | 0.82 | LMNA (0.59) | LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023279-A | Mechanochemical synthesis of a radiographic intermediate | 伯拉考成像股份公司 | 2019-07-16 | — | — | CN | disclosed |
| EP-1112247-B1 | A PROCESS FOR THE PREPARATION OF S-N,N'-BIS 2-HYDROXY-1- (HYDROXYMETHYL) ETHYL]-5- (2-HYDROXY-1- OXOPROPYL) AMINO]-2,4,6- TRIIODO-1,3- BENZENEDICARBOXAMIDE | BRACCO IMAGING SPA (IT) | 2003-04-16 | — | — | EP | disclosed |
| EP-1112247-A1 | A PROCESS FOR THE PREPARATION OF S-N,N'-BIS 2-HYDROXY-1- (HYDROXYMETHYL) ETHYL]-5- (2-HYDROXY-1- OXOPROPYL) AMINO]-2,4,6- TRIIODO-1,3- BENZENEDICARBOXAMIDE | BRACCO IMAGING S.p.A. (IT) | 2001-07-04 | — | — | EP | disclosed |