Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7581413 | 1.00 | LMNA (0.42) | LMNASMN1; SMN2KLK7HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL7071547 | 0.98 | LMNA (0.41) | LMNASMN1; SMN2KLK7HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL7581432 | 0.98 | LMNA (0.41) | LMNASMN1; SMN2KLK7HDAC3HDAC4 | |
| SCHEMBL15760479 | 0.96 | LMNA (0.40) | LMNASMN1; SMN2KLK7HDAC3HDAC4 | |
| SCHEMBL17066747 | 0.91 | LMNA (0.36) | LMNASMN1; SMN2KLK7HDAC3HDAC4 | |
| SCHEMBL14181569 | 0.89 | LMNA (0.41) | LMNAKLK7HDAC3HDAC4HDAC1 | |
| SCHEMBL5356462 | 0.86 | LMNA (0.40) | LMNAKLK7TSHR | |
| SCHEMBL8586708 | 0.86 | LMNA (0.43) | LMNASMN1; SMN2KLK7HDAC3HDAC4 | |
| SCHEMBL6879887 | 0.86 | LMNA (0.40) | LMNAKLK7TSHR | |
| SCHEMBL5482338 | 0.86 | LMNA (0.40) | LMNAKLK7TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2723709-B1 | MANUFACTURE OF A TRIIODINATED CONTRAST AGENT | HOVIONE INT LTD (CH) | 2015-09-09 | — | — | EP | claimed |
| US-8835672-B2 | Manufacture of a triiodinated contrast agent | HOVIONE INTER LIMITED (CH) | 2014-09-16 | — | — | US | claimed |
| US-20140155648-A1 | Manufacture of a Triiodinated Contrast Agent | HOVIONE INTER LIMITED (CH) | 2014-06-05 | — | — | US | claimed |
| EP-2723709-A1 | MANUFACTURE OF A TRIIODINATED CONTRAST AGENT | Hovione Inter Ltd. (CH) | 2014-04-30 | — | — | EP | claimed |
| WO-2012175903-A1 | MANUFACTURE OF A TRIIODINATED CONTRAST AGENT | HOVIONE INTER. LTD (CH) | 2012-12-27 | — | — | WO | claimed |
| EP-3580199-B1 | METHOD FOR THE ONE-POT PRODUCTION OF ORGANO-IODINATED COMPOUNDS | GUERBET SA (FR) | 2023-04-05 | — | — | EP | disclosed |
| US-10836711-B2 | Method for the one-pot production of organo-iodinated compounds | GUERBET (FR) | 2020-11-17 | — | — | US | disclosed |
| CN-107445858-A | The production of triiodide contrast agent | 霍维奥恩联合有限公司 | 2017-12-08 | — | — | CN | disclosed |
| EP-2723709-B1 | MANUFACTURE OF A TRIIODINATED CONTRAST AGENT | HOVIONE INT LTD (CH) | 2015-09-09 | — | — | EP | disclosed |
| EP-2723709-B1 | MANUFACTURE OF A TRIIODINATED CONTRAST AGENT | HOVIONE INT LTD (CH) | 2015-09-09 | — | — | EP | disclosed |
| US-8835672-B2 | Manufacture of a triiodinated contrast agent | HOVIONE INTER LIMITED (CH) | 2014-09-16 | — | — | US | disclosed |
| US-8835672-B2 | Manufacture of a triiodinated contrast agent | HOVIONE INTER LIMITED (CH) | 2014-09-16 | — | — | US | disclosed |
| EP-2723709-A1 | MANUFACTURE OF A TRIIODINATED CONTRAST AGENT | Hovione Inter Ltd. (CH) | 2014-04-30 | — | — | EP | disclosed |
| EP-2723709-A1 | MANUFACTURE OF A TRIIODINATED CONTRAST AGENT | Hovione Inter Ltd. (CH) | 2014-04-30 | — | — | EP | disclosed |
| WO-2012175903-A1 | MANUFACTURE OF A TRIIODINATED CONTRAST AGENT | HOVIONE INTER. LTD (CH) | 2012-12-27 | — | — | WO | disclosed |
| WO-2012175903-A1 | MANUFACTURE OF A TRIIODINATED CONTRAST AGENT | HOVIONE INTER. LTD (CH) | 2012-12-27 | — | — | WO | disclosed |
| EP-0901460-B1 | A PROCESS FOR THE PREPARATION OF 5-AMINO-2,4,6-TRIIODO-1,3-BENZENEDICARBOXYLIC ACID DERIVATIVES | BRACCO IMAGING SPA (IT) | 2002-09-18 | — | — | EP | disclosed |
| EP-0773925-A1 | PROCESS FOR THE PREPARATION OF A DICARBOXYLIC ACID DICHLORIDE | Fructamine S.P.A. (IT) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996037460-A1 | PROCESS FOR THE PREPARATION OF A DICARBOXYLIC ACID DICHLORIDE | FRUCTAMINE S.P.A. (IT) | 1996-11-28 | — | — | WO | disclosed |
| US-4364921-A | RADIOPACITY | SCHERING, AKTIENGESELLSCHAFT (DE) | 1982-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10836711-B2 | Method for the one-pot production of organo-iodinated compounds | TPO, NISCH, PPIP5K2 | LMNA 3525/4885SMN1; SMN2 4729/4885KLK7 601/4885 |
| US-20140155648-A1 | Manufacture of a Triiodinated Contrast Agent | SAT1, LYPLA2, AGPAT5 | LMNA 2871/4885SMN1; SMN2 4778/4885KLK7 2958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.