Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 6/20 | 0.41 |
| ▸ | F2 | P00734 | 4/20 | 0.39 |
| ▸ | F10 | P00742 | 4/20 | 0.39 |
| ▸ | PLAT | P00750 | 4/20 | 0.39 |
| ▸ | PLG | P00747 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7799865 | 0.98 | PLAU (0.40) | PLAUF2F10PLATPLG | |
| SCHEMBL7797852 | 0.77 | PLAU (0.39) | PLAUF2F10PLATPLG | |
| Hydrochloric Acid SCHEMBL7791934 | 0.76 | PLAU (0.38) | PLAUF2F10PLATPLG | |
| SCHEMBL1043966 | 0.73 | TP53 (0.45) | TP53TSHR | |
| SCHEMBL8430498 | 0.72 | GPR35 (0.36) | — | |
| SCHEMBL7797783 | 0.72 | SLC9A1 (0.45) | PLAU | |
| Hydrochloric Acid SCHEMBL8336402 | 0.71 | GPR35 (0.35) | — | |
| SCHEMBL7952054 | 0.71 | CFTR (0.42) | TSHR | |
| Hydrochloric Acid SCHEMBL7799870 | 0.71 | SLC9A1 (0.44) | PLAU | |
| SCHEMBL28549913 | 0.68 | MEN1 (0.39) | PLAUF2F10PLATPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794172-B1 | Orthosubstituted benzoylguanidines | HOECHST AG (DE) | 2001-10-24 | — | — | EP | claimed |
| US-6262123-B1 | AS ANTIARRHYTHMIC AGENTS HAVING CARDIOPROTECTIVE COMPONENT, FOR PROPHYLAXIS AND TREATMENT OF INFARCTION AND ANGINA PECTORIS; FOR INHIBITION OF PATHOPHYSIOLOGICAL PROCESSES ASSOCIATED WITH GENESIS OF ISCHEMICALLY INDUCED DAMAGE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-07-17 | — | — | US | claimed |