Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | PLG | P00747 | 2/20 | 0.36 |
| ▸ | PLAT | P00750 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7791934 | 0.98 | PLAU (0.38) | PLAUF2F10PLGPLAT | |
| SCHEMBL7797854 | 0.78 | TMPRSS4 (0.41) | PLAUF2F10PLGPLAT | |
| SCHEMBL7797776 | 0.77 | PLAU (0.41) | PLAUF2F10PLGPLAT | |
| Hydrochloric Acid SCHEMBL7791912 | 0.77 | TMPRSS4 (0.40) | PLAUF2F10PLGPLAT | |
| Hydrochloric Acid SCHEMBL7799865 | 0.76 | PLAU (0.40) | PLAUF2F10PLGPLAT | |
| SCHEMBL23875335 | 0.74 | P2RX1 (0.57) | MAPTMEN1KMT2AKCNMA1CA1 | |
| SCHEMBL7799854 | 0.74 | PYGL (0.46) | ALDH1A1MAPTKDM4EPYGLGAA | |
| Hydrochloric Acid SCHEMBL8392493 | 0.74 | ALDH1A1 (0.62) | ALDH1A1MAPTKDM4EMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL8393884 | 0.74 | KDM4E (0.62) | ALDH1A1MAPTKDM4EPYGLGAA | |
| Hydrochloric Acid SCHEMBL7797878 | 0.73 | PYGL (0.45) | ALDH1A1MAPTKDM4EPYGLGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794172-B1 | Orthosubstituted benzoylguanidines | HOECHST AG (DE) | 2001-10-24 | — | — | EP | claimed |
| US-6262123-B1 | AS ANTIARRHYTHMIC AGENTS HAVING CARDIOPROTECTIVE COMPONENT, FOR PROPHYLAXIS AND TREATMENT OF INFARCTION AND ANGINA PECTORIS; FOR INHIBITION OF PATHOPHYSIOLOGICAL PROCESSES ASSOCIATED WITH GENESIS OF ISCHEMICALLY INDUCED DAMAGE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-07-17 | — | — | US | claimed |